A pair of recent studies led by Joseph Mazzulli, PhD, have uncovered previously unknown cellular mechanisms involved in neuronal protein aggregation and misfolding, key characteristics of Parkinson’s disease, which may serve as therapeutic targets.
Northwestern investigators have identified a novel transcription factor which regulates a signaling mechanism utilized by a fertilized embryo to protect its mother from cellular and environmental stress, according to a recent study to published in the journal Genes and Development.
Inflamed heart muscles can mount immune responses even in the absence of immune cells, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
Northwestern Medicine scientists have discovered that a weakened form of a virus can be used to help eliminate cancer in mice.
A dysfunctional enzyme may lead to nonalcoholic fatty liver disease in mice, according to a study published in Science Advances.
Northwestern Medicine scientists have discovered a way to regenerate damaged heart muscle cells in mice, a development which may provide a new avenue for treating congenital heart defects, according to a study published in the Journal of Clinical Investigation.
The surge in RSV cases following the COVID-19 pandemic may have been, in part, caused by increased testing and changes to the RSV genome, according to a Northwestern Medicine study published in Nature Communications.
A large international team of scientists have uncovered genetic risk factors for multiple system atrophy, according to a study published in Neuron.
A new gene therapy could revolutionize treatment for two rare genetic blood disorders, according to a pair of trials published in the New England Journal of Medicine.
Investigators have discovered new mechanisms underlying intratumor heterogeneity and treatment resistance in meningiomas, the most common type of primary central nervous system tumor, according to a recent study published in Nature Genetics.
