Category: Disease Discoveries
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Parkinson’s Gene Linked to Early Dysfunction in Brain Cells
Northwestern Medicine scientists have uncovered how a major Parkinson’s disease gene disrupts the brain’s most vulnerable dopamine-producing neurons before detectable neuronal loss, according to findings published in Nature Communications.
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Study Identifies New Genetic Variants that Cause Rare Tumor Disorder
A recent Northwestern Medicine study offers new data showing previously unknown genetic variants that cause the development of tuberous sclerosis complex, a rare genetic disorder that causes benign tumors to develop in many parts of the body, according to findings published in Nature Communications.
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AI-Guided Study Uncovers Drug Targets for Psoriasis
A new study from Northwestern Medicine investigators, in collaboration with Biohub, a program of the Chan Zuckerberg Initiative, has identified potential drug targets for treating psoriasis, according to the study published in Nature Communications.
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‘Leaky’ Muscle Fibers Drive Immune Response in Muscular Dystrophy
A Northwestern Medicine study has uncovered how chronic defects in muscle membrane repair can fuel harmful inflammation, according to the study published in JCI Insight.
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Daylight Saving Time Impacts Risk of Retinal Vascular Disease
For the first time, Northwestern Medicine scientists have detailed how autumn and spring daylight saving time transitions impact a person’s risk of developing retinal vascular disease, according to a recent study published in Scientific Reports.
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Radiotherapy Reprograms Immune Response in Rare Skin Cancer
A new Northwestern Medicine study has discovered how radiotherapy alters the immune environment within cutaneous T-cell lymphoma tumors, revealing new molecular signatures associated with long-term treatment response and tumor recurrence.
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Intricate Molecular Mechanisms Help Bacteria Evade Immune Detection
Northwestern scientists have identified a novel mechanism utilized by the bacteria responsible for gonorrhea to evade immune detection and achieve widespread infection, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Immunotherapy Strategy Shows Promise for Deadly Brain Cancer
A new immunotherapy strategy has shown promise in targeting one of the most aggressive and deadly forms of brain cancer, according to a new study published in Nature.
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Understudied Enzyme Helps Pathogen Prosper, Study Finds
A new study published in the Proceedings of the National Academy of Sciences has offered insight into how Staphylococcus aureus, a major human pathogen, fine-tunes its internal RNA degradation machinery to survive stress and potentially cause infection.
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Identifying Immune Pathways Driving Aggressive Brain Cancers
A new study has uncovered a key mechanism that helps one of the deadliest brain cancers evade the immune system, according to the study published in The Journal of Clinical Investigation.
