Category: Disease Discoveries
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Non-Neuron Brain Cells Produce a Third of Amyloid Plaque in Alzheimer’s Disease
An international team of investigators have discovered that oligodendrocytes contribute approximately one-third of plaque formation alongside neurons in mouse models of Alzheimer’s disease, according to a recent study published in Nature Neuroscience.
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Oncoprotein Activity Increases Prostate Cancer Progression
Investigators have discovered that aberrant activation of a specific oncoprotein drives key tumor promoting changes in the prostate tissue microenvironment during cancer progression, according to a Northwestern Medicine study published in Nature Communications.
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Older Adults in Illinois at Increased Risk for Suicide
Nearly 20 percent of suicides in Illinois between 2020 and 2021 were among people 65 years and older, according to recently released data.
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Understanding Structural Drivers of HIV and Substance Use
The NIH recently funded the five-year SILOS Project, led by principal investigator Michelle Birkett, PhD, which will conduct innovative observational research across five cities across the United States to better understand the social contexts that drive HIV and substance use.
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Intense Exercise Doesn’t Increase Risk of Sudden Death in Genetic Heart Disorder
High-intensity exercise does not increase the risk of sudden cardiac death in individuals with congenital long-QT syndrome, a genetic heart disorder, according to findings from a recent study published in Circulation.
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Study Identifies Racial Differences in Rare Endometrial Cancer
Northwestern Medicine investigators have discovered that uterine serous carcinoma tumors in Black patients express more aggressive and immunosuppressive features than tumors in white patients, according to a recent study published in the Proceedings of the National Academy of Sciences.
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‘Hidden’ Irregular Heartbeats May Raise Risk of Death
Irregular heartbeats can raise a person’s risk of death even when they go unnoticed by traditional heart monitoring, according to a Northwestern Medicine study published in Circulation.
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Analyzing the Effects of Dietary Acculturation on Heart Health
Dietary acculturation may increase the risk of heart disease for people of Hispanic or Latino heritage in the U.S., according to a study published in Circulation.
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Study Finds Noncoding RNAs Dysregulated in Several Human Cancers
Northwestern Medicine scientists have discovered new insights into the production and regulation of an emerging class of noncoding RNAs in three major types of cancer, according to findings published in Science Advances.
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Scientists Discover Potential Biomarker in Rare Skin Cancer
Northwestern Medicine scientists have discovered increased immune cell activity in Merkel cell carcinoma tumors, which could help predict treatment response in patients and inform the development of new targeted therapies, according to findings published in the journal Cancer Discovery.
