Category: Clinical Breakthroughs
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Combination Therapy Shows Promise in High-Risk Prostate Cancer, Study Finds
A large international clinical trial has found that adding the drug apalutamide to standard hormone therapy before and after prostate cancer surgery significantly improves outcomes for men with high-risk disease, according to details published in The New England Journal of Medicine.
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New GLP-1 Drug Promotes Weight Loss in Obesity
A new strategy for delivering GLP-1 drugs to patients with obesity or who were overweight resulted in up to an 11 percent reduction in body weight after 36 weeks, according to a randomized phase II clinical trial published in Nature Medicine.
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Cryoprobe Improves Diagnostic Accuracy and Safety in Lung Biopsies
Transbronchial lung biopsy procedures performed with a 1.1 millimeter cryoprobe demonstrated higher diagnostic accuracy and safety than two-millimeter forceps in patients with lung nodules or masses and lung transplant, according to a recent randomized trial published in JAMA.
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One in Three Middle-Aged Adults Struggle With Basic, ‘Everyday’ Health Tasks
One in three middle-aged American adults ages 35 to 64 cannot consistently read prescription instructions correctly, understand medical forms or recall details from doctor visits involving chronic condition diagnoses, according to a recent study.
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Expanding the Evidence for Behavioral Interventions in Gastroenterology
The Division of Gastroenterology and Hepatology at Feinberg has a distinct strength in understanding how behavior and lifestyle influence gastrointestinal (GI) health. The Division conducts research aimed at improving treatments for disorders of the digestive tract and related organs.
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Novel Synthetic Biomolecule Degrades Disease-Related Proteins
Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can target and degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches for a wide range of diseases, as detailed in a recent study.
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Study Uncovers Potential Gene Therapy for Late-Stage Parkinson’s Side-Effects
Northwestern Medicine scientists have discovered that suppressing excitatory synaptic transmission in a small group of neurons in the brain may reverse levodopa-induced dyskinesia in patients with late-stage Parkinson’s disease without reducing the symptomatic benefits of levodopa treatment, according to a recent study published in Neuron.
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Asthma Drug Improves Treatment of Aggressive Cancers in Preclinical Studies
A drug widely used to treat asthma and allergies may also help fight aggressive cancers, reports a new Northwestern Medicine study that uncovered how tumors hijack common white blood cells to evade immunotherapy.
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Wearable Polygraph Detects Hidden Stress
Northwestern University engineers have developed a small, wireless polygraph system you can wear, designed to sense underlying stress hidden deep within the body.
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Building Capacity for Research in Ukraine
Two Feinberg investigators, Sara Huston, MS, and Steven P. Cohen, MD, have been collaborating with scientists in Ukraine to better understand how war is impacting Ukrainians through inquiries into DNA use for family reunification and better treating amputees’ pain.
