Tag: Research
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FDA-Approved Compound Promotes Neuroprotective Effects in Parkinson’s Disease
Northwestern Medicine scientists have discovered an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson’s disease, according to a recent study published in The Journal of Clinical Investigation.
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Calcium Signaling Channels Regulate Neuroinflammation and Motivation
Northwestern Medicine scientists have discovered how calcium signaling channels in the brain’s immune cells regulate neuroinflammation and promote the development of behaviors associated with affective mood disorders, according to a recent study published in Science Signaling.
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First Gene Regulation Clinical Trials for Epilepsy Show Promising Results
A first‑ever gene‑regulation therapy tested in early‑phase clinical trials co‑led by Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children’s Hospital of Chicago has proven safe in children with Dravet syndrome who have exhausted conventional treatment options, according to a study published in the New England Journal of Medicine.
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Automated Screening and Education Increases Urinary Incontinence Diagnoses
Implementing an automated urinary incontinence screening and educational program in primary care practices significantly increased awareness and treatment referrals in women with the condition, according to a recent study published in JAMA Internal Medicine.
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Circadian Rhythm Causes Metabolic Dysfunction in Fat Cells
Northwestern Medicine scientists have discovered how disruptions in circadian rhythm impair metabolic function in fat cells, providing new insights into the molecular mechanisms that cause obesity and metabolic disease, according to a recent study published in Nature Metabolism.
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CAR T-cell Therapy Improves Survival in Relapsed or Refractory Lymphoma
CAR T-cell immunotherapy improved progression-free and overall survival in patients with relapsed or refractory marginal zone lymphoma, according to a recent clinical trial published in The Lancet.
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Trashing Cancer’s ‘Undruggable’ Proteins
Northwestern scientists have developed polymers capable of grabbing proteins and directing them to the cell’s waste-disposal machinery, potentially triggering cancer cell death.
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AI Model Predicts Language Development in Children with Hearing Loss
An advanced machine learning model predicted spoken language outcomes in children who received cochlear implants more accurately than traditional machine learning approaches, according to a recent Northwestern Medicine-led international multi-center study.
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As Superagers Age, They Make at Least Twice as Many New Neurons as Their Peers
New research shows that the brains of “SuperAgers” continue to generate new neurons in the hippocampus at levels far higher than typical older adults, and even much younger individuals.
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Living ‘Mini Brains’ Meet Next-Generation Bioelectronics
A team led by Northwestern University and Shirley Ryan AbilityLab scientists have developed a new technology that can eavesdrop on the hidden electrical dialogues unfolding inside miniature, lab-grown human brain-like tissues.
