Tag: Research
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New Experimental Method Reveals Protein Energy Landscapes on Larger Scale
Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein domains on a uniquely large scale, which may improve data-driven modeling, biology and protein engineering, as detailed in a recent study published in Nature.
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Spatial Transcriptomics Guides Inflammatory Bowel Disease Research
A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the development of inflammatory bowel diseases, as detailed in a recent study published in Nature Communications.
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Building Capacity for Research in Ukraine
Two Feinberg investigators, Sara Huston, MS, and Steven P. Cohen, MD, have been collaborating with scientists in Ukraine to better understand how war is impacting Ukrainians through inquiries into DNA use for family reunification and better treating amputees’ pain.
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Skin-Resident Immune Cells Drive Neuropathic Pain in Diabetes
In experimental models of diabetes, Northwestern Medicine scientists have discovered that a specialized group of skin-resident immune cells drive neuropathic pain through sex-dependent signaling pathways, according to a recent study published in The Journal of Clinical Investigation.
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ALS is Driven by a Domino‑Like Chain Reaction That Begins in Nerve Cells
A new Northwestern Medicine study provides evidence that ALS unfolds through a domino‑like sequence of events that begins with an early breakdown inside motor neurons and is followed by a damaging inflammatory response.
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Metformin Slows Mitochondrial Energy Production, Promotes Glycemic Control
A new Northwestern Medicine study has found that metformin, a commonly prescribed diabetes drug, focuses primarily on the gut, acting to prevent glucose levels rising in the blood by driving glucose utilization inside cells lining the intestine.
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Time-Restricted Eating Supports Weight Loss in Women with PCOS
A time-restricted eating program promoted greater weight loss in women with polycystic ovary syndrome (PCOS) than no intervention, according to a randomized controlled trial published in Nature Medicine.
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Treatment of Rare Childhood Epilepsy Could Begin Before Birth
A new Northwestern study suggests that interventions for epilepsy can start during pregnancy, as early as 15 weeks gestation, well before symptoms appear, according to a study published in Nature Communications.
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Reinfection Raises Long COVID Risk in Children and Adolescents
Children and adolescents who are reinfected with SARS-CoV-2 face a significantly higher risk of developing long COVID, according to a large, multi-institutional study published in The Lancet Infectious Diseases.
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New Tool Collects Biology Data into Cellular Atlases
A new computational method could dramatically accelerate efforts to map the body’s cells in space, according to a study published in Nature Genetics.
