Tag: Pharmacology
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Exploring the Molecular Mechanisms of Ion Channels and Kidney Disease
Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
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Study Demonstrates How the Brain Moves Neuroreceptors
Northwestern Medicine scientists identified the mechanism that transports important neuroreceptors from sites outside to within the synapse, publishing their findings in Cell Reports.
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Uncovering Enzyme’s Dual Role in Cancer Suppression and Growth
A new Northwestern Medicine study has uncovered how a key enzyme in mitochondria can function as both a cancer suppressor and cancer promoter.
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Calcium Channels Play Essential Role in Astrocyte Activity
Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.
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Scientists Identify Function of Alzheimer’s Protein
A team of scientists has discovered the physiological function of APP, a protein long known to be associated with Alzheimer’s disease but whose normal function had remained elusive.
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New Inhibitor Improves Autism-Like Symptoms in Mice
A Northwestern University experimental therapeutic targeting a specific protein kinase reversed neurological symptoms in a mouse genetic model of autism, according to a recent Northwestern Medicine study.
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New Insights Into Cancer Metastasis
Northwestern Medicine scientists have discovered how circulating tumor cells cluster together during metastasis — findings that reveal a novel mechanism for how cancer spreads and a potential new target for treatment.
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Inherited Genetic Variants Associated With Bleeding on Common Anticoagulant
According to a recent study, a group of four gene mutations seen only in people with African ancestry may contribute to an increased risk of severe bleeding while taking warfarin.
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Disrupting Gene Transcription Elongation to Treat Cancer
Targeting cancer cells with a transcription elongation inhibitor delayed tumor progression in animal models, according to a recent Northwestern Medicine study.
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Carvill Receives NIH New Innovator Award
Gemma Carvill, PhD, assistant professor of Neurology, has been named a recipient of the NIH Director’s New Innovator Award, which funds highly innovative research proposals with the potential to transform their field.
