Tag: Pharmacology
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Sexual Dysfunction Inadequately Reported In Hair Loss Drug Trials For Men
Male baldness clinical trials did not adequately report sexual dysfunction, which may persist long-term, according to a Northwestern Medicine meta-analysis of published reports of clinical trials of the drug finasteride.
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Evaluating Drugs to Improve Vision In Diabetic Macular Edema
A new Northwestern Medicine study published in the New England Journal of Medicine shows the drug Eylea is superior to other options for improving the eyesight of persons with poor vision due to diabetic macular edema, a major cause of diabetes-related vision loss.
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Grant Funds Classification of Disease-Causing Genetic Mutations
A $5 million grant from the National Institutes of Health will support research to determine the functional and structural consequences of genetic mutations associated with a dangerous heart condition.
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Calcium Channel Discovery Unlocks Brain Therapy Options
Scientists from Northwestern Medicine have discovered a key function for the CRAC channel, which transports calcium into cells.
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Drug Discovery Screening 100 Times Faster
Milan Mrksich, PhD, professor in the Department of Cell and Molecular Biology, has created a tool and a startup company to test biological reactions quickly and cheaply.
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A Place for Drug Discovery
Al George, MD, Melds Genetics, Drug Discovery To Personalize Medicine
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Drug Halts Protein Known to Affect Aging
The experimental drug prolonged the lifespan in a mouse model of accelerated aging by inhibiting a protein that plays a key role in the process.
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Iron May be at Heart of Cancer Drug’s Cardiotoxicity Effect
Hossein Ardehali, MD, PhD, has discovered that doxorubicin, an effective and commonly used anticancer drug, is causing an accumulation of iron inside of a cell’s mitochondria, resulting in heart damage.
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Ion Channel Expert to Head Pharmacology
Most recently the chief of genetic medicine and director of the Institute for Integrative Genomics at Vanderbilt University, Alfred L. George Jr., MD, arrives at Feinberg on March 1, 2014.
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Mechanism Behind Monitoring of Neuromuscular Blockers Discovered
Published in Anesthesiology, Eugene Silinsky, PhD, has found that calcium channels, and not a depletion of neurotransmitters as previously thought, are responsible for the decreased response in muscles treated by neuromuscular blockers. The finding could prove helpful in developing new therapies for a host of neuromuscular diseases.
