Tag: Pharmacology
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Unravelling the Mysteries of Calcium Channel Regulation
Scientists have uncovered new insights into the molecular players behind calcium channel regulation, a biological process that coordinates a wide array of physiological responses, according to a study published in the Proceedings of the National Academy of Sciences.
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New Huntington’s Treatment Prevents Protein Aggregation in Mice
In research published in Science Advances, scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington’s disease, an incurable, debilitating illness that causes nerve cells to break down in the brain.
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Little-Studied RNA Might be Key to Regulating Genetic Disorders Like Epilepsy, Autism
Scientists have discovered an RNA that controls how much or how little protein is produced by a gene, with implications for neurodevelopmental disorders like epilepsy and autism.
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Genetic Mechanisms May Reveal Retinal Vascular Disease Therapeutic Targets
Northwestern Medicine investigators have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve as therapeutic targets for retinal vascular disease, according to findings published in Nature Communications.
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Feinberg Scientists to Lead Grant Studying Autism, Schizophrenia
Northwestern Medicine scientists have been awarded $17 million to study genetic causes of autism and schizophrenia, with the aim of developing new drugs to treat the conditions.
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Improving Models to Study the Human Heart
Northwestern Medicine scientists have developed a new method of measuring and optimizing the maturation process of cultured heart cells, an approach that will set the future standard for a commonly used cell model in scientific research, according to details published in Cell Reports.
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Deploying Polygenic Risk Scores in Primary Care Settings
A multi-institutional team of investigators have developed a new framework for supporting healthcare providers in implementing polygenic risk score-based testing into primary care settings, according to a recent study published in Nature Medicine.
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Uncovering the Mysteries of Microproteins
Northwestern Medicine scientists have developed a method to identify and characterize microproteins, a development which opens the door for understanding physiology and disease at a molecular level not possible until now, according to findings published in Nature Communications.
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Engineered Heart Cells May Improve Understanding of Atrial Fibrillation
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
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Novel Pathway Explains the Escalation of Fear Responses
Scientists have discovered a neuronal pathway involved in how the brain encodes the transition to high-intensity fear response behaviors required for survival, according to a study published in Nature.
