Tag: Pharmacology
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A New Clue to ALS and FTD: Faulty Protein Disrupts Brain’s ‘Brake’ System
A new Northwestern study has uncovered how a key disease protein drives overactive nerve cells in neurodegenerative diseases like ALS and frontotemporal dementia.
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Smith Honored with NIH New Innovator Award
Richard Smith, PhD, assistant professor of Pharmacology and of Pediatrics, has received the National Institutes of Health (NIH) Director’s New Innovator Award, which supports early-career investigators conducting high-risk and innovative research in the biomedical, behavioral or social sciences.
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Investigating How Tumor-Immune Cell Clusters Drive Cancer Spread
In a pair of studies, investigators from the lab of Huiping Liu, MD, PhD, have uncovered how specific cellular interactions in the bloodstream may be fueling the spread of breast cancer.
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Successful Gene Editing Demonstrated for a Rare Neurodevelopmental Disorder
Scientists have implemented a novel gene-editing approach that may be an effective treatment for alternating hemiplegia of childhood (AHC), a rare neurodevelopmental disorder in children, according to a recent study published in Cell.
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Novel Molecular Mechanisms Inform Targeted Therapies for Chronic Kidney Disease
A recent Northwestern Medicine study has identified novel molecular mechanisms by which genetic mutations in the PKD2 gene cause the most common type of polycystic kidney disease, according to findings published in Proceedings of the National Academy of Sciences.
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Identifying New Therapeutic Strategies for Psychiatric Disorders
A new Northwestern Medicine study has identified the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson’s disease symptoms, according to findings published in Molecular Psychiatry.
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Novel Approach Improves Protein Characterization in Human Tissue
Scientists have developed a novel, robust proteomics technique that can more accurately identify and spatially characterize thousands of proteins in single cells within human tissue samples, as detailed in a recent study published in Nature Communications.
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Potential Therapeutic Targets for Genetic Heart Disorder Discovered
Investigators from Northwestern University Feinberg School of Medicine and Vanderbilt University School of Medicine have discovered new molecular mechanisms behind a genetic heart disorder that can increase the risk of sudden death in children and young adults, according to a recent study published in PNAS.
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Uncovering New Therapeutic Targets for Pediatric Epilepsy
Investigators in the laboratory of Gemma Carvill, PhD, have discovered novel molecular underpinnings of Dravet syndrome, a rare genetic form of epilepsy in children, that may serve as promising therapeutic targets, according to a recent study.
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Unravelling the Mysteries of Calcium Channel Regulation
Scientists have uncovered new insights into the molecular players behind calcium channel regulation, a biological process that coordinates a wide array of physiological responses, according to a study published in the Proceedings of the National Academy of Sciences.
