Scientists Identify Structural Changes in Herpesvirus Fusion
Northwestern and Stanford scientists have uncovered new details on the structure of herpesviruses that allow them to initiate a fusion event to infect host cells.
Browsing: "Microbiology"
2010 Cholera Epidemic Linked to Hypervirulent Strain
Northwestern Medicine scientists have discovered that the cholera strain responsible for the 2010 epidemic in Haiti is a hypervirulent variant.
Uncovering How Refolding Proteins Allow Viruses to Enter Cells
Northwestern Medicine scientists discovered a crucial element underlying how proteins on the surface of enveloped viruses such as measles and mumps undergo a process that allows the virus to enter host cells.
Student Explores Encephalitis in the Newborn Brain
Douglas Wilcox, a student in the Medical Scientist Training Program, discovered the herpes simplex virus targets a host cell protein to cause severe disease and encephalitis in newborns.
Investigating How Cholera Bacteria Toxins Inhibit Autophagy
A new Northwestern Medicine study highlighted for the first time how a toxin from the extracellular bacterium Vibrio cholerae can inhibit autophagy and endosomal trafficking.
Tracking How Herpes Simplex Virus Moves Through Cells
Northwestern Medicine scientists showed how the herpes simplex virus exploits microtubule plus-end tracking proteins to move within human cells, providing insights into how viruses engage with host transport networks.
Uncovering How Herpes Viruses Invade the Nervous System
A new study demonstrates how herpes viruses switch between two invasive states to promote infection in the nervous system.
Graduate Student Investigates the Role of Proteins in Immune Cell Development
Kyle O’Hagan, a graduate student in the Driskill Graduate Program in Life Sciences, studies Pak2, a protein essential in the development of a subset of immune cells called regulatory T-cells.
Uncovering the Spread of Bacteria in Pneumonia
Northwestern Medicine scientists have revealed how a pneumonia-causing bacterium uses a toxin to spread itself from the lungs to the bloodstream.
Feinberg Student Explores the Pathogenesis of Ocular Herpes Infection
Rebecca Edwards, an MD/PhD student, studies the role host factors play in mediating disease in the eye caused by the herpes simplex virus type 1.