Northwestern and Stanford scientists have uncovered new details on the structure of herpesviruses that allow them to initiate a fusion event to infect host cells.
Northwestern Medicine scientists have discovered that the cholera strain responsible for the 2010 epidemic in Haiti is a hypervirulent variant.
Northwestern Medicine scientists discovered a crucial element underlying how proteins on the surface of enveloped viruses such as measles and mumps undergo a process that allows the virus to enter host cells.
Douglas Wilcox, a student in the Medical Scientist Training Program, discovered the herpes simplex virus targets a host cell protein to cause severe disease and encephalitis in newborns.
A new Northwestern Medicine study highlighted for the first time how a toxin from the extracellular bacterium Vibrio cholerae can inhibit autophagy and endosomal trafficking.
Northwestern Medicine scientists showed how the herpes simplex virus exploits microtubule plus-end tracking proteins to move within human cells, providing insights into how viruses engage with host transport networks.
A new study demonstrates how herpes viruses switch between two invasive states to promote infection in the nervous system.
Kyle O’Hagan, a graduate student in the Driskill Graduate Program in Life Sciences, studies Pak2, a protein essential in the development of a subset of immune cells called regulatory T-cells.
Northwestern Medicine scientists have revealed how a pneumonia-causing bacterium uses a toxin to spread itself from the lungs to the bloodstream.
Rebecca Edwards, an MD/PhD student, studies the role host factors play in mediating disease in the eye caused by the herpes simplex virus type 1.