Northwestern Medicine scientists discovered a crucial element underlying how proteins on the surface of enveloped viruses such as measles and mumps undergo a process that allows the virus to enter host cells.
Douglas Wilcox, a student in the Medical Scientist Training Program, discovered the herpes simplex virus targets a host cell protein to cause severe disease and encephalitis in newborns.
A new Northwestern Medicine study highlighted for the first time how a toxin from the extracellular bacterium Vibrio cholerae can inhibit autophagy and endosomal trafficking.
Northwestern Medicine scientists showed how the herpes simplex virus exploits microtubule plus-end tracking proteins to move within human cells, providing insights into how viruses engage with host transport networks.
A new study demonstrates how herpes viruses switch between two invasive states to promote infection in the nervous system.
Kyle O’Hagan, a graduate student in the Driskill Graduate Program in Life Sciences, studies Pak2, a protein essential in the development of a subset of immune cells called regulatory T-cells.
Northwestern Medicine scientists have revealed how a pneumonia-causing bacterium uses a toxin to spread itself from the lungs to the bloodstream.
Rebecca Edwards, an MD/PhD student, studies the role host factors play in mediating disease in the eye caused by the herpes simplex virus type 1.
A new study suggests a toxin responsible for seafood-associated sepsis and necrotizing fasciitis may have the ability to treat cancer by destroying the protein Ras.
Northwestern Medicine scientists identified an important mechanism that regulates replication of the human papillomavirus.