Tag: Immunology
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Investigating Mechanisms Behind Early HIV-1 Infection
Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection.
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Hypoxic Inflammation Blunts Repair After Heart Attack
Inefficient cardiac repair after heart attacks is partially driven by a maladapted response to a low oxygen environment by immune cells, according to a study published in the Journal of Experimental Medicine.
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Study Explores Possible Therapeutic Target for SARS-CoV-2
Inhibiting a specific protein complex in SARS-CoV-2, the virus that causes COVID-19, may be a promising therapeutic target for treating the disease, according to a Northwestern Medicine study.
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Miller Receives Biomaterials Award for Celiac Disease Nanoparticle Therapy
Stephen Miller, PhD, received the 2021 Technology Innovation and Development Award from the Society For Biomaterials for work on a nanoparticle that induces gluten tolerance in celiac disease.
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Inflammation Protection May Be Critical to Treating MS
Prolonging a cellular defense response to inflammation could help regenerate the protective coating of axons that is degraded in diseases such as multiple sclerosis, according to a recent study.
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Immune Receptor Linked to Chronic Heart Transplant Rejection
The AXL immune cell receptor has been linked to cardiac allograft vasculopathy, a thickening of vessel walls in transplanted hearts years after implantation, according to a recent study.
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Changes in Macrophages Drive Vulnerability to Lung Infections
An age-related accumulation of a signaling molecule may be one culprit behind older adults’ vulnerability to viral pneumonias, according to a recent study.
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Viral Protein Rewires B-Cells to Promote Infection
A viral protein of the Epstein-Barr virus previously thought to mimic immune cell receptor signaling actually rewires intracellular signaling in infected cells, promoting viral cell survival and proliferation.
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Improving Immunotherapy For Breast Cancer
Treatment-resistant breast cancer could be made vulnerable to immunotherapy by flipping a metabolic “switch,” according to a new Northwestern Medicine study.
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Utilizing B-Cells to Promote Glioblastoma Immunity
Northwestern investigators have developed a novel vaccine that utilizes a specialized group of B-cells to promote anti-tumor immunity against glioblastoma.
