Tag: Genetics
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Gene Implicated in Poor Skin Cancer Therapy Outcomes
Losing a check on T-cell activation in cutaneous T-cell lymphoma cells is associated with poor outcomes, according to a study published in Blood.
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Using Circulating Tumor DNA to Target Immunotherapy
Using circulating tumor DNA to identify patients at risk for urothelial cancer relapse after surgical resection could help improve post-surgery treatment, according to a new study.
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New Method to Untangle 3D Cancer Genome
Northwestern Medicine scientists have described a method of reconstructing the three-dimensional structure of chromosomes in cancer cells and matching those chromosomes with counterpart oncogenes.
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New Method to Analyze Nucleosomes
Northwestern Medicine scientists have developed Nuc-MS, a new method to capture the protein composition of whole nucleosomes without losing information.
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Mitochondria Play Key Role in Lymphatic Development
Mitochondria play a key role in forming the lymphatic vasculature by acting as a metabolic sensor during the migration of lymphatic progenitor cells from the veins.
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Uncovering the Function of Prostate Cancer Protein
Northwestern Medicine scientists have discovered a mechanism that makes a prostate cancer-causing protein called FOXA1 more resilient, according to a recent study.
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The XX/XY Factor
A massive trove of information produced in a Northwestern-led study will lay the groundwork for understanding sex-related differences in health and disease for decades to come.
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Next-Gen Sequencing
Northwestern’s investment in next-generation sequencing is leading to unprecedented avenues of discovery.
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New Genetic Cause of Dystonia Revealed
Northwestern Medicine scientists discovered mutations in a scaffolding protein contributes to dystonia, an incurable movement disorder.
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Predicting the Severity of Cardiomyopathy via Genetic Modifiers
A team of Northwestern Medicine investigators have identified specific genetic regions that regulate the expression of genes associated with inherited cardiomyopathy and disease severity.
