Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder.
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template.
Genomic autopsy of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy.
Losing a check on T-cell activation in cutaneous T-cell lymphoma cells is associated with poor outcomes, according to a study published in Blood.
Using circulating tumor DNA to identify patients at risk for urothelial cancer relapse after surgical resection could help improve post-surgery treatment, according to a new study.
Northwestern Medicine scientists have described a method of reconstructing the three-dimensional structure of chromosomes in cancer cells and matching those chromosomes with counterpart oncogenes.
Northwestern Medicine scientists have developed Nuc-MS, a new method to capture the protein composition of whole nucleosomes without losing information.
Mitochondria play a key role in forming the lymphatic vasculature by acting as a metabolic sensor during the migration of lymphatic progenitor cells from the veins.
Northwestern Medicine scientists have discovered a mechanism that makes a prostate cancer-causing protein called FOXA1 more resilient, according to a recent study.