Tag: Genetics
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Telomere Changes Predict Cancer
A distinct pattern in the changing lengths of telomeres years before cancer diagnoses could yield a new biomarker that predict cancer, according to a new study.
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Structure of Parainfluenza Virus 5 Reveals How Replication Occurs
Northwestern Medicine scientists have for the first time, determined the protective structure of the parainfluenza virus 5 nucleocapsid ring, which hides the viral RNA genetic material from the outside environment. These findings may help to explain how the virus and other membrane-enveloped viruses including measles and mumps replicate with minimal changes to the protective ring…
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Nanotech-Enabled Moisturizer Speeds Healing Of Diabetic Skin Wounds
New Northwestern Medicine research shows spherical nucleic acids can silence a gene that interferes with wound healing, opening the door to new treatments for diabetic skin wounds, as well as many other conditions.
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Cancer Genes Turned Off in Deadly Brain Cancer
Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM) when delivered using spherical nucleic acid nanoparticles.
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Accelerating Natural Product Discovery for Biomedical Research
Northwestern Medicine scientists have developed a method to systematically explore diverse natural resources, allowing them to quickly identify thousands of compounds from bacteria that have potential to become new pharmaceuticals.
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Uncovering Genetic Roots of Pediatric Kidney Tumor
A Northwestern Medicine study has identified new genetic mutations in patients with Wilms tumor, the most common kidney tumor in children.
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DNA Transcription Sheds Light on Cancer Pathogenesis
In several recent publications, Ali Shilatifard, PhD, chair of Biochemistry and Molecular Genetics, examined how different aspects of transcriptional regulation are involved in cancer development.
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New Human Enzyme Provides Genetic Link to Gestational Diabetes
A new study from Northwestern Medicine and Duke University has identified an enzyme that may be a genetic predictor for whether an expectant mother develops hyperglycemia.
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Connecting Cellular Aging to Human Aging
A Northwestern Medicine study has linked aging at the cellular level to overall human aging through a molecular interaction involving two proteins and chromosome ends called telomeres.
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Considering Whole Genome Sequencing for Newborns
In a recent Northwestern Medicine exploratory study, genetics experts considered incorporating whole genome sequencing into traditional newborn screening, revealing varying opinions about handling the future of genomics.
