Tag: Cancer
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Bioinformatic Computational Tool Analyzes Tissue Samples to Discern Disease
A novel integrative computational technique allowed scientists to classify disease conditions at the molecular level using epigenomic data sets.
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Northwestern Scientists Discover Potential Therapeutic Target for Glioblastoma
Northwestern Medicine investigators have discovered that inhibiting tumor-associated myeloid cells ability to produce specialized metabolites called polyamines may improve the effectiveness of treatments for glioblastoma.
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Antibody Bolsters Immune Response to Glioblastoma
Northwestern Medicine scientists have engineered a novel antibody that revitalizes immune cell activity in a deadly brain cancer, according to a recent study.
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New Spherical Nucleic Acid ‘Drug’ Kills Tumor Cells in Humans With Glioblastoma
An experimental spherical nucleic acid drug developed by Northwestern scientists was able to penetrate the blood-brain barrier and trigger the death of glioblastoma cells.
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Evaluating Perioperative Chemotherapy for Pancreatic Cancer
Perioperative chemotherapy treatment did not improve overall survival for patients with resectable pancreatic cancer, according to a recent Northwestern Medicine clinical trial.
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Blocking Cell Division in Glioblastoma
Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
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Identifying Therapeutic Targets for B-cell Acute Lymphoblastic Leukemia
Northwestern Medicine investigators have identified a protein kinase called DYRK1A and its downstream substrates as potential therapeutic targets for treating pediatric patients with B-cell acute lymphoblastic leukemia.
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Antibody Drug Improves Survival for Aggressive Breast Cancer
A new antibody drug demonstrated similar efficacy to currently available therapies to treat advanced ERBB2-positive breast cancer, according to a recent clinical trial.
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Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
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Uncovering How Protein Complexes Impact Gene Expression
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
