Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
Northwestern Medicine scientists have discovered a new biomarker to identify which patients with brain tumors called glioblastomas — the most common and malignant of primary brain tumors — might benefit from immunotherapy.
Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs.
A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a Merit Extension Award from the National Cancer Institute, one of only two Comprehensive Cancer Centers in the nation to earn the recognition.
From teasing out determinants of health disparities to developing precision medicine treatments, clinicians and scientists from the Lurie Cancer Center are dramatically changing the landscape for all men with prostate cancer.
The underexpression of a specific metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma, which accounts for 80 percent of all kidney cancers, according to a recent study.
Tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell immunotherapy, demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia, according to recent findings.