Newly Discovered Protein Explains Leukemia’s Treatment Resistance
Northwestern scientists recently identified a new protein complex that is upregulated in acute myeloid leukemia, potentially explaining why current therapies are often ineffective.
Browsing: "Biochemistry"
Uncovering Mechanisms of Cellular Growth and Division
A new study has uncovered a key mechanism underlying the control of a co-factor that is essential for all cells to grow and divide, and which may also play a key role in cancer cell growth.
Study Suggests New Strategy to Treat Advanced Prostate Cancer
A Northwestern Medicine study provides new insights into a signaling pathway in metastatic prostate cancer and suggests that a novel drug combination may improve treatment response and slow cancer growth.
Mitochondria Linked to Autoimmunity
Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.
Pediatric Leukemia ‘Super Drug’ Could be Developed in Coming Years
Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, the first step towards a pediatric leukemia “super drug.”
New Understanding of Enzyme’s Role in Prostate Cancer
Northwestern Medicine scientists have discovered that an enzyme called EZH2 can activate expression of the androgen receptor gene, which drives prostate cancer growth.
New Regulator of Leukemia Discovered
Inhibiting CHAF1B, a protein that normally helps replenish blood cells, may be a promising treatment for leukemia, according to a recent study.
New Therapeutic Target Identified in Prostate Cancer
A Northwestern Medicine study has revealed new insights into a pathway in prostate cancer and identified a potential new therapeutic target for aggressive disease.
Chromosome Domain Inherits Information Without Using DNA Sequence
A recent study found that stability of chromatin structures across DNA replication requires cooperation between a histone chaperone and DNA replication machinery; a mechanism of epigenetic inheritance.
Cancer Crusader
Leon Platanias steers the Lurie Cancer Center toward better patient outcomes. Read the story in Northwestern Medicine magazine.