Northwestern scientists recently identified a new protein complex that is upregulated in acute myeloid leukemia, potentially explaining why current therapies are often ineffective.
A new study has uncovered a key mechanism underlying the control of a co-factor that is essential for all cells to grow and divide, and which may also play a key role in cancer cell growth.
A Northwestern Medicine study provides new insights into a signaling pathway in metastatic prostate cancer and suggests that a novel drug combination may improve treatment response and slow cancer growth.
Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.
Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, the first step towards a pediatric leukemia “super drug.”
Northwestern Medicine scientists have discovered that an enzyme called EZH2 can activate expression of the androgen receptor gene, which drives prostate cancer growth.
Inhibiting CHAF1B, a protein that normally helps replenish blood cells, may be a promising treatment for leukemia, according to a recent study.
A Northwestern Medicine study has revealed new insights into a pathway in prostate cancer and identified a potential new therapeutic target for aggressive disease.
A recent study found that stability of chromatin structures across DNA replication requires cooperation between a histone chaperone and DNA replication machinery; a mechanism of epigenetic inheritance.