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Improving Treatment for Hairy Cell Leukemia
Patients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent response and relapse-free survival, according to a recent clinical trial published in Blood.
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Novel Cell ‘Switches’ Promote Lung Cancer Growth, Treatment Resistance
Northwestern Medicine investigators have revealed new insights into how cell type switches facilitate tumor growth and treatment resistance in small cell lung cancer, according to findings published in Science Advances.
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Identifying New Genetic Variants Linked to Heart Failure
Scientists have identified new genes linked to heart failure, according to a study published in Nature Communications.
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Direct-to-Consumer Online Platforms Expand Access, but Often Fail to Convey Risks of Testosterone Therapy
Direct-to-consumer platforms for testosterone therapy don’t always provide care in concordance with professional guidelines, according to a recent Northwestern Medicine study.
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Exploring Genetic Regulation of Immunoglobulin A
Increased levels of the antibody immunoglobulin A (IgA) are correlated with the manifestation of several diseases and African ancestry, according to findings published in Nature Communications.
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Investigating Quality of Life in Large B-cell Lymphoma
Patient-reported outcomes in relapsed or refractory large B-cell lymphoma revealed that receiving CAR T-cell immunotherapy was associated with higher quality of life, according to a recent study.
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2022 Year in Review
Feinberg experienced a year of outstanding growth, scientific achievement, and collaboration in 2022, from honors and awards to unprecedented research discoveries.
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Northwestern Investigators Develop New Therapy for Autism Subtype
A team of Northwestern investigators led by Peter Penzes, PhD, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder.
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A Day in the Life: Medical Student Kai Brady
Meet Kai Brady, a second-year MD student at Feinberg School of Medicine, and get a look at a typical day during this phase of her medical school career.
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2022 IPHAM Forum Celebrates a Long History of Public Health at Northwestern
The Institute for Public Health and Medicine recently hosted its annual Population Health Forum, a celebration of the ten-year anniversary of the institute that brought together hundreds of public health researchers, trainees, and community partners.
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OB-GYN Research Lacks Racial, Ethnic Inclusivity
Non-white racial and ethnic groups are underrepresented in OB-GYN clinical trials, according to a new Northwestern Medicine study.
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Study Uncovers Potential Therapeutic Approach for Advanced Prostate Cancer
A Northwestern Medicine study has discovered that elevated PALI1 in advanced prostate tumors mediates crosstalk between two primary epigenetic silencing mechanisms, suggesting that dual epigenetic inhibition may be an effective therapeutic strategy.
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Top 3 Breakthroughs Podcasts of 2022
The Breakthroughs podcast released more than 20 episodes in 2022 on topics ranging from the role of dopamine in habit formation to music-based medical interventions.
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Personalized T-cell Therapy Improves Immune Response Against Cancer
Investigators have developed a novel personalized T-cell therapy approach that may identify specific targets unique to a patient’s cancer cells more effectively than current treatments, according to findings published in Nature.
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Watterson Elected to National Academy of Inventors
Daniel Martin Watterson, PhD, the John G. Searle Professor of Molecular Biology and Biochemistry, has been named a 2022 fellow of the National Academy of Inventors.
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Study Identifies New Therapeutic Target for Tumor Treatment
Northwestern Medicine scientists have identified a new therapeutic target against tumor cells and developed a compound which slows tumor growth and bolsters immune response.
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Investigating Disparities in Machine Learning Algorithms
Integrating social determinants of health helped mitigate bias when predicting long-term outcomes for heart failure patients, according to a Northwestern Medicine study.
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Study Identifies Two Genes Linked to Microcephaly
Northwestern Medicine scientists have identified pathogenic variants in two genes linked to microcephaly and other neurodevelopmental disorders in children, according to a recent study published in Nature Communications.
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New Immune Culprit Discovered in Alzheimer’s Disease
A new Northwestern Medicine study has discovered the role of cerebrospinal fluid in cognitive impairment, such as Alzheimer’s disease.
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Aging Is Driven by Unbalanced Genes
In a new study, Northwestern investigators used artificial intelligence to analyze data from a wide variety of tissues, and discovered that the length of genes can explain most molecular-level changes that occur during aging.
