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Bone Transcription Factor Controls Nervous System Gene Expression
An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, according to a Northwestern Medicine study published in Neuron.
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Evolving Telehealth Research and its Place in Healthcare Delivery
Since the COVID-19 pandemic thrust many providers into telehealth appointments, scientists have been asking questions about the benefits and concerns of telehealth. While telehealth was in use and gathering interest prior to the pandemic, the need for it accelerated during a time when people were encouraged to stay home.
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Global Health Day Highlights Pandemic, HIV Research
Northwestern investigators, faculty, students and community partners came together to share and celebrate global health research, education and outreach as part of the Robert J. Havey, MD Institute for Global Health’s 12th annual Global Health Day.
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AI May Spare Breast Cancer Patients Unnecessary Treatments
A new AI tool may make it possible to spare breast cancer patients unnecessary chemotherapy treatments by using a more precise method of predicting their outcomes, reports a new Northwestern Medicine study published in Nature Medicine.
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Drug Extends Survival in Prostate Cancer with Genetic Mutations
Men with hormone-resistant prostate cancer and specific genetic mutations who were treated with the drug olaparib survived longer than men treated with traditional hormone therapy, according to a post hoc analysis published in the Journal of Clinical Oncology.
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Pioneering Biochemist Craig Crews Named Winner of 2024 Kimberly Prize
Northwestern University Feinberg School of Medicine and the Simpson Querrey Institute for Epigenetics announced today that renowned biochemist Craig M. Crews, PhD, who pioneered the pharmaceutical field of targeted protein degradation, has been named the winner of the annual $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
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Family Language Tied to Hospitalization Rates in Feverish Babies
Babies of parents who speak a language other than English may be more likely to be unnecessarily hospitalized when visiting the emergency department for high fevers, according to a recent study published in JAMA Pediatrics.
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New Therapeutic Strategies for Spinal Muscular Atrophy
Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences (PNAS).
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Investigating Drug Combinations for Heart Failure
A common diabetes medication may help some patients with treatment-resistant hypertension slightly lower their high blood pressure and lessen their risk of heart failure events such as stroke, according to an analysis of a clinical trial published in Circulation.
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Comparing Cardiac Monitoring Methods to Detect Atrial Fibrillation After Stroke
Insertable cardiac monitors detected a higher incidence of atrial fibrillation in patients with prior ischemic stroke over a three-year period than standard medical monitoring methods, according to results published in JAMA Neurology, based on long-term findings from the Northwestern Medicine-led STROKE AF clinical trial.
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Using Gene Expression to Predict if a Brain Tumor is Likely to Grow Back
Scientists have found a highly accurate way to predict the best cancer treatment for patients based on patterns of gene expression in their tumors.
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Immigrants Living in the U.S. Have Fewer Preterm Births
Individuals born in the U.S. had a higher rate of giving birth prematurely compared to U.S. immigrants, a new Northwestern Medicine study has found.
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Feinberg Investigators Recognized on 2023 ‘Highly-Cited’ List
Twelve Feinberg faculty members were named to the 2023 “Highly Cited Researchers” list, published by Clarivate Analytics. The annual list identifies investigators who have demonstrated significant influence in their field through the publication of highly cited publications during the last decade.
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Aortic Valve Replacement Procedures Show Similar Long-Term Survival Rates
Patients with severe aortic stenosis who underwent a minimally invasive aortic valve replacement procedure had similar long-term survival rates compared to patients who underwent traditional surgery, according to a recent study published in The New England Journal of Medicine.
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New Human Gene Cluster Sequence Discovered
Investigators from the laboratory of Ali Shilatifard, PhD, have discovered a new repeat gene cluster sequence that is exclusively expressed in humans and non-human primates, according to findings published in Science Advances.
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Understanding Healthcare Worker Collaboration and Patient Outcomes
Some interventions designed to improve healthcare worker collaboration may not improve patient outcomes, according to a recent trial published in the Annals of Internal Medicine.
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Novel Wearables Capture Body Sounds to Continuously Monitor Health
Northwestern scientists are introducing new soft, miniaturized wearable devices that continuously track subtle sounds simultaneously and wirelessly at multiple locations across nearly any region of the body.
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Predicting The Risk of Heart Disease — 10 Years Younger Than Before
For the first time in 10 years, the American Heart Association has updated the model to predict someone’s risk of developing heart disease.
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Novel Approaches for Correcting Gene Expression Insufficiency
A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by insufficient protein levels, according to a study published in Nature Communications.
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Investigating the Pathogenesis of Rare Congenital Nerve Disorder
A new Northwestern Medicine study has uncovered previously unidentified intracellular mechanisms in the peripheral nervous system that cause Charcot–Marie–Tooth Type 2B disease, findings that may inform the development of new targeted therapies.
