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Novel Regulator of Immune Evasion in Cancer Identified
Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
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Neural Mechanisms May Serve as Therapeutic Target for Depression
A recent study published in Molecular Psychiatry has identified previously unknown alterations in neural connectivity that promote psychomotor disturbance — a slowing or reduction in movement — in individuals with major depressive disorder.
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Mustanski Appointed as Advisor to NIH Director
Brian Mustanski, PhD, director of the Institute for Sexual and Gender Minority Health and Wellbeing, has been appointed to the Advisory Committee to the Director of National Institutes of Health.
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Subset of Neurons Allow Eyes to Detect Motion
Northwestern Medicine scientists have identified how a subset of neurons enable the eyes to perceive motion, according to a study published in Nature Communications, a discovery that reveals previously hidden complexities of how vision functions in mammals.
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Building Momentum Toward Neural Prostheses
Several recent studies from Feinberg investigators and colleagues have shed light on complex neurological processes and provided new insights and technological developments for neural prostheses.
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Kwasny Recognized by the American Statistical Association
Mary Kwasny, ScD, professor of Preventive Medicine in the Division of Biostatistics, has received the American Statistical Association’s (ASA) Founders Award, the highest award the organization bestows for distinguished service.
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Exploring How Antibiotic-Resistant Bacteria Become Aggressive
Some strains of an antibiotic-resistant bacteria may not turn out to be as aggressive as previously thought, according to a Northwestern Medicine study recently published in Nature Communications.
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Defining Rheumatoid Arthritis Subtypes May Improve Treatments
By profiling the inflammatory cells types in joint tissue biopsy samples, scientists have characterized six subtypes of rheumatoid arthritis, an approach that could help physicians tailor more effective treatment strategies for patients based on disease type, according to findings published in Nature.
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New Brain-Like Transistor Mimics Human Intelligence
Taking inspiration from the human brain, scientists have developed a new synaptic transistor capable of higher-level thinking, according to results published in the journal Nature.
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Novel ‘Feeding’ Mechanism Promotes Glioblastoma Treatment Resistance
Northwestern Medicine investigators have discovered that specialized immune cells within the glioblastoma tumor microenvironment use a unique “feeding” mechanism that promotes tumor growth and treatment resistance, according to findings published in the journal Cell Metabolism.
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2023 Year in Review
Feinberg experienced a year of outstanding growth, scientific achievement, and collaboration in 2023, from honors and awards to unprecedented research discoveries.
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Localized Genetic Mutations May Serve as Biomarker for Wide Range of Cancers
Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification and treatment, according to findings published in Proceedings of the National Academy of Sciences.
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Study Discovers Novel Biomarker for Vascular Aging and Neurodegeneration
Decreased activity of a specific signaling pathway in the brain vessels of aging mice and humans was linked to a decline in vascular function and subsequent neurodegeneration, according to a recent Northwestern Medicine study published in the Journal of Clinical Investigation.
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Semaglutide Trials Show Improvements in Cardiovascular Health, Quality of Life
Two years after the FDA’s approval of semaglutide for chronic weight management, Northwestern Medicine scientists remain at the forefront of investigating the drug’s potential in helping patients who are overweight or have obesity who also have other preexisting health conditions.
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Exploring How Poxviruses Dismantle Antiviral Responses
Northwestern Medicine investigators led by Derek Walsh, PhD, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, according to findings published in Nature Communications.
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Feinberg Names New Associate Dean for Student Affairs
Eli Zimmerman, MD, has been named associate dean for student affairs at Feinberg, effective January 1, 2024.
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Top 3 Breakthroughs Podcasts of 2023
The Breakthroughs podcast released 19 episodes in 2023 on topics ranging from implementation science and ChatGPT to new insights in dopamine and AI in healthcare. The top three most downloaded episodes this year were on varying topics including exercise and Parkinson’s disease, food allergies and recent discoveries about mitochondria.
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Developing Deep Learning Models to Understand the Human Genome
Northwestern Medicine scientists have developed a deep learning algorithm accelerating research around diseases and disorders that occur when the process of DNA transcription goes awry.
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Medical Student Variety Show Supports Chicago Street Medicine
Medical students shared laughs and poked fun at the medical school experience during the annual performance of In Vivo, Feinberg’s sketch comedy and variety show, held on December 8.
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Krainc, Kelley Elected to National Academy of Inventors
Dimitri Krainc, MD, PhD, the Aaron Montgomery Ward Professor and chair of the Davee Department of Neurology and director of the Simpson Querrey Center for Neurogenetics, has been elected to the National Academy of Inventors.
