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Epigenetic ‘Priming’ Boosts Cancer Immunotherapy
An epigenetic inhibitor increased immune system activity in patients with ovarian cancer.
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Most Common Lung Function Test Misses Lung Disease in Many Black U.S. Adults
The most common test to measure a person’s lung function may be missing many people with impaired lung health, according to a new study.
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Identifying Therapeutic Targets for Chemotherapy-Resistant Glioblastoma
Investigators have discovered novel cellular pathways behind chemotherapy-resistant glioblastoma cells and a potential biomarker, paving the way for new therapeutic targets.
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Investigators Explore Cellular Response to Stress
Northwestern Medicine investigators have discovered novel mechanisms that regulate cellular stress response, according to findings published in the Proceedings of the National Academy of Sciences.
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Light During Sleep in Older Adults Linked to Obesity, Diabetes, High Blood Pressure
Exposure to light during sleep was associated with obesity, diabetes and high blood pressure in older adults, according to a recent study.
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Brain Lesion Location Influences Addiction Behaviors
Damage to particular regions of the brain may influence addiction behaviors, providing insight into potential therapeutic targets for substance use disorders.
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Crohn’s Antibodies Equally Effective
Two new treatments for Crohn’s disease showed roughly equal performance in a clinical trial.
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NUCATS Town Hall Offers Overview of Resources and Renewal Efforts
The Northwestern University Clinical and Translational Sciences Institute delivered an overview of resources and efforts targeted at the upcoming 2023 renewal at a recent town hall.
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Northwestern Panel Examines Implications of Abortion Ruling
The Supreme Court’s decision in Dobbs v. Jackson will have significant implications for access to pregnancy-related healthcare, according to a recent Northwestern panel discussion.
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Levitsky Selected as President-elect of American Society of Transplantation
Josh Levitsky, MD, ’08 MS, has been selected as president-elect of the American Society of Transplantation (AST).
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Targeting Bicarbonate in Cancer
Bicarbonate ions are required for cell growth in some cancers, according to a Northwestern Medicine study.
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Medical Student Investigates Genetic Diversity in Lung Cancer
Stas Fridland, a rising third-year medical student, investigated genetic differences in solid lung cancer tumors and clinical outcomes for his Area of Scholarly Concentration (AOSC) project.
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Weekly Symptom Monitoring Improves Quality of Life in Cancer
In adult patients undergoing cancer treatment, weekly electronic symptom monitoring significantly improved quality of life, according to a recent study published in JAMA.
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Reducing Blood Cultures and Antibiotics in Pediatrics
Multidisciplinary diagnostic stewardship programs safely decreased blood culture collection and antibiotics for pediatric intensive care patients, according to findings published in JAMA Pediatrics.
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Anti-seizure Medication has a New Target
Designed to target AMPAR receptors in the brain, the medication — called perampanel — also modulates kainate receptors.
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Dual Function Found for mRNA Modifier
An enzymatic modifier of messenger RNA has different functions depending on its location, according to a recent study.
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Physician Assistant Students Embrace ‘Shades of Purple’
Rosalia Garcia and Kristin Brennan, students in the PA Program, lead the Shades of Purple program, a bimonthly discussion group that covers the intricacies of care for differently abled or diverse patients.
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Dissolving Implantable Device Relieves Pain Without Drugs
A Northwestern University-led team has developed a small, pain-relieving implant that could provide a much-needed alternative to opioids and other highly addictive medications.
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Fathers’ Presence During Childhood Predicts Adult Testosterone Levels
The presence and involvement of fathers with their sons during childhood predicted the profile of adult testosterone levels, according to a recent study.
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Epigenetic Biomarkers Predict CVD Risk
A new study provides evidence that blood epigenetic biomarkers contain “snapshots” of past cardiovascular health exposures and behavior at the molecular level.
