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Predicting Which Glioblastoma Patients Will Respond to Immunotherapy
Northwestern Medicine scientists have discovered a new biomarker to identify which patients with brain tumors called glioblastomas — the most common and malignant of primary brain tumors — might benefit from immunotherapy.
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$12.5 Million to Fund ALS Research at Northwestern
Neurodegenerative Disease Research Inc. has made a five-year, $12.5 million philanthropic commitment to Northwestern to support research in amyotrophic lateral sclerosis (ALS) led by Teepu Siddique, MD.
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Northwestern Scientists Investigate COVID-19 Vaccines, Tests and Disparities
Northwestern Medicine scientists continue to tackle every facet of the COVID-19 pandemic, from investigating coronavirus vaccines’ potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.
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Drug May Benefit Patients with Heart Failure
Dapagliflozin, a drug commonly used to treat type 2 diabetes, improved heart failure-related symptoms and physical limitations in patients with heart failure with preserved ejection fraction.
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Identifying Cancer Biomarkers for Immunotherapy Response
Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs.
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Combination Therapy Reduces Toxic Aggregates in Parkinson’s Disease
A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
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NUPOC Students Create Teddy Bear Braces for Lurie Children’s Patients
On November 5, students in the Master of Prosthetics & Orthotics (MPO) program through Northwestern’s Prosthetics-Orthotics Center constructed more than 50 braces for teddy bears gifted to pediatric patients at Ann & Robert H. Lurie Children’s Hospital.
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Respiratory Virus Reprograms Airway Epithelial Cells
Respiratory syncytial virus infection during infancy results in metabolic reprogramming in epithelial cells lining the airway, according to a recent study.
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How Herpes Checks Into the Nervous System for Life
A new Northwestern Medicine study has uncovered herpes’ sneaky strategy for infecting the nervous system, opening a path to long-needed vaccine development for the virus.
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Northwestern Receives Grant to Support Equity in Biomedicine
Northwestern University Feinberg School of Medicine has been awarded a $550,000 grant to support the retention of early-career clinician investigators experiencing family caregiving challenges due to the COVID-19 pandemic.
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Drug May Improve Cardiac Function in Hypertrophic Cardiomyopathy
Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to a recent clinical trial.
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Neurobiologists Identify a New Gene Important for Healthy Daily Rhythms
A recent study identified a gene that is critical for daily behavioral rhythms, involved in a molecular pathway by which the core circadian clock controls daily sleep-wake cycles.
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Inge Joins Lurie Children’s Hospital as Surgeon-in-Chief
Ann & Robert H. Lurie Children’s Hospital of Chicago has recruited an internationally recognized surgeon-scientist, Thomas H. Inge, MD, PhD, as the hospital’s next surgeon-in-chief.
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New Insights into Cell Polarity
A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.
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‘Dancing Molecules’ Successfully Repair Severe Spinal Cord Injuries
A new injectable therapy harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries, allowing animal subjects to regain the ability to walk.
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Students Practice Ophthalmology Surgical Techniques
The student-led Ophthalmology Interest Group recently held a suturing workshop, offering Feinberg students the opportunity to practice surgical techniques on mock organs.
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Study Shows Epigenetic Modification is Central for Tumor Metastasis
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
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Second-year Students Present AOSC Projects
Second-year medical students presented Area of Scholarly Concentration (AOSC) research projects during a virtual session held November 5.
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Northwestern Medicine Investigators Receive $14 Million Grant to Study Viral Pneumonia
An interdisciplinary team of Northwestern Medicine investigators led by Karen Ridge, PhD, has been awarded a $14 million grant from the National Heart, Lung, and Blood Institute to study the mechanisms that promote lung tissue repair in patients with severe viral pneumonia.
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New Insights into the Mechanism of ALS
The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
