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Understanding Inflammation in the Heart
Inflamed heart muscles can mount immune responses even in the absence of immune cells, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
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Improving Advanced Care Planning for Late-Stage Cancer
Multilevel care interventions improved clinician–documented advanced care planning compared with a clinician-level intervention alone for patients with genitourinary cancer, according to recent findings published in JAMA Oncology.
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Investigating DNA Flexibility for the Creation of New Biomaterials
Northwestern investigators have demonstrated how manipulating DNA chemistry can alter its structure and flexibility and enable the realization of new materials useful in medicine and the life sciences, according to a study published in Science Advances.
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Common Blood Pressure Drug May Increase Risk of Bleeding
People with irregular heartbeats taking a common blood pressure drug may be at greater risk of serious bleeding, according to a study recently published in JAMA.
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Goyal and Kennedy Named 2024 Pew Scholars
Yogesh Goyal, PhD, and Ann Kennedy, PhD, have been named 2024 Pew Scholars by The Pew Charitable Trusts, which recognizes promising early-career investigators whose research will accelerate discovery and translation in the biomedical sciences.
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ASN Names Quaggin Winner of the John P. Peters Award
The American Society of Nephrology has announced Susan Quaggin, MD, the Irving S. Cutter Professor and chair of Medicine, as the winner of the 2024 John P. Peters Award.
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Drug Reprograms Immune Responses to Target Glioblastoma
Investigators have discovered that using a novel drug agonist to target the STING pathway in preclinical models of glioblastoma reprogrammed previously suppressed immune responses, according to recent findings published in the Journal of Clinical Investigation.
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Transplant Research Thrives Through Collaboration
A map of the Northwestern University Transplant Outcomes Research Collaborative (NUTORC) Network looks like an intricate spiderweb. Hovering over one investigator’s name, you see the many investigators they are connected with through publications and research collaboration.
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Combination Therapy Shows Promise in Subset of Breast Cancers
Combining two cancer drugs may be a promising treatment for advanced metastatic breast cancer, according to the results of a clinical trial published in the Journal of Clinical Oncology.
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Weakened Virus Helps Eliminate Cancer
Northwestern Medicine scientists have discovered that a weakened form of a virus can be used to help eliminate cancer in mice.
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Dysfunctional Enzyme May Lead to Liver Disease
A dysfunctional enzyme may lead to nonalcoholic fatty liver disease in mice, according to a study published in Science Advances.
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Novel Drug May Improve Oxygen Uptake in Hypertrophic Cardiomyopathy
Patients with obstructive hypertrophic cardiomyopathy who received a new drug demonstrated improved oxygen uptake and exercise tolerance, according to a study published in the New England Journal of Medicine.
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Genetic Mechanisms May Reveal Retinal Vascular Disease Therapeutic Targets
Northwestern Medicine investigators have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve as therapeutic targets for retinal vascular disease, according to findings published in Nature Communications.
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Antioxidant Gel Preserves Islet Function After Pancreas Removal
Northwestern University scientists have developed a novel antioxidant biomaterial that someday could provide much-needed relief to people living with chronic pancreatitis, according to a new study published in Science Advances.
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New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer Cells
Northwestern Medicine scientists have used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy, a major advance for the treatment of this deadly cancer.
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Mittal Announces He is Stepping Down as Chair of Radiation Oncology
Bharat B. Mittal, MD, the William N. Brand, MD, Professor of Radiation Oncology, has announced that he will be stepping down as chair of the department of Radiation Oncology.
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Utilizing Electronic Alerts to Help Control Blood Pressure
Nudges from an electronic health record system reminding physicians to prescribe hypertension drugs to patients with chronic kidney disease led to improved blood pressure management, according to a clinical trial published in JAMA Internal Medicine.
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Mesulam Center Celebrates 30th Annual Alzheimer Day
The Mesulam Center for Cognitive Neurology and Alzheimer’s Disease celebrated its 30th Annual Alzheimer’s Day on May 3, 2024, where researchers and community members came together to learn about recent accomplishments in the field, early-onset Alzheimer’s and community efforts raising awareness for those experiencing cognitive decline.
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Foltz Named New Director of Driskill Graduate Program
Dan Foltz, PhD, professor of Biochemistry and Molecular Genetics, has been named director of the Walter S. and Lucienne Driskill Graduate Program in Life Sciences (DGP). He will begin the role on July 1.
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Feinberg Scientists to Lead Grant Studying Autism, Schizophrenia
Northwestern Medicine scientists have been awarded $17 million to study genetic causes of autism and schizophrenia, with the aim of developing new drugs to treat the conditions.