Category: Disease Discoveries
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Uncovering Genetic Roots of Pediatric Kidney Tumor
A Northwestern Medicine study has identified new genetic mutations in patients with Wilms tumor, the most common kidney tumor in children.
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Alzheimer Amyloid Clumps Found in Young Adult Brains
A Northwestern medicine study found accumulations of amyloid in young adult brains, the first time accumulation of amyloid has been shown at such a young age.
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DNA Transcription Sheds Light on Cancer Pathogenesis
In several recent publications, Ali Shilatifard, PhD, chair of Biochemistry and Molecular Genetics, examined how different aspects of transcriptional regulation are involved in cancer development.
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Exploring Age-Related Differences in Herpes Encephalitis
Northwestern Medicine scientists have revealed age-dependent differences in cellular mechanisms for protection from herpes simplex virus encephalitis.
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Auditory Pain Pathway May Protect Against Hearing Loss
Northwestern Medicine scientists have discovered a novel pain pathway in the inner ear that warns of dangerously loud noise and may act as a “bodyguard” for the ears, protecting against hearing loss.
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New Human Enzyme Provides Genetic Link to Gestational Diabetes
A new study from Northwestern Medicine and Duke University has identified an enzyme that may be a genetic predictor for whether an expectant mother develops hyperglycemia.
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Fat Tissue May Be Key to Scleroderma’s Progression
Northwestern Medicine scientists have discovered that scar-forming cells in scleroderma come from fat tissue within layers of the skin, a new cellular origin that could be a key to developing treatments for the incurable disease.
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SuperAger Brains Yield New Clues To Their Remarkable Memories
Brains of elderly patients with very sharp memories – patients known as cognitive SuperAgers – look distinctly different than their elderly peers, according to a new Northwestern Medicine study.
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Legionnaires’ Disease Provides New Insights on Bacterial Systems
Northwestern Medicine scientists demonstrated the ability of a protein, Cas2, in Legionella pneumophila to cleave nucleic acids resulting in increased infectivity in amoebae, its host organism and transmission vehicle for human infection of Legionnaires’ disease.
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Exploring Upper Motor Neuron Degeneration in ALS
Northwestern Medicine scientists have revealed a mechanism underlying the cellular degeneration of the upper motor neurons that die in ALS, and developed a model system that will allow further research on the degeneration.
