Category: Disease Discoveries
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Promoting Stem Cells to Repair Neurons in Multiple Sclerosis
Northwestern Medicine scientists have identified two drugs that stimulate stem cells in the central nervous system with the potential to repair the protective coating around neurons damaged in multiple sclerosis.
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Uncovering Mechanisms of Replication in Human Papillomavirus
Northwestern Medicine scientists identified an important mechanism that regulates replication of the human papillomavirus.
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Protein Protects Organs From Immune Damage
Northwestern Medicine scientists have identified a previously unknown key regulator of immune response, a protein kinase called Jnk2 that helps maintain cellular homeostasis through a series of physiological processes.
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Stem Cell Biology the Focus for New ALS Lab
Evangelos Kiskinis, PhD, assistant professor in Neurology and Physiology, uses stem cells to study the motor neurons and genes implicated in ALS.
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Telomere Changes Predict Cancer
A distinct pattern in the changing lengths of telomeres years before cancer diagnoses could yield a new biomarker that predict cancer, according to a new study.
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Vimentin Implicated in Lung Inflammation and Fibrosis
A new Northwestern Medicine study shows that a protein called vimentin may help activate an inflammatory response that leads to acute lung injury.
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Northwestern Medicine Researchers Solve Mystery of Deadly Transplant Infection
Northwestern Medicine scientists have identified a specific bacteria that may be the cause of a rare lung infection that affects lung transplant patients.
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Structure of Parainfluenza Virus 5 Reveals How Replication Occurs
Northwestern Medicine scientists have for the first time, determined the protective structure of the parainfluenza virus 5 nucleocapsid ring, which hides the viral RNA genetic material from the outside environment. These findings may help to explain how the virus and other membrane-enveloped viruses including measles and mumps replicate with minimal changes to the protective ring[…]
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Tracking HIV to the Cell Nucleus
Northwestern Medicine scientists explored how HIV uses host factor FEZ-1 to move in cells to the nucleus.
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Pathway Signals Motor Neuron Death in Spinal Muscular Atrophy
Northwestern Medicine scientists have found a signaling pathway that contributes to motor neuron degeneration in spinal muscular atrophy, and may help to better understand other neurodegenerative disorders.
