Category: Disease Discoveries
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Targeting STING Pathway Triggers Cytotoxic and Immune Responses Against Meningioma
Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Communications.
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HPV Cancer Vaccine Slows Tumor Growth, Extends Survival in Preclinical Model
Northwestern scientists have discovered that systematically changing the orientation and placement of a single cancer-targeting peptide can lead to drug formulations that supercharge the immune system’s ability to attack tumors.
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Paralysis Treatment Heals Lab-Grown Human Spinal Cord Organoids
Using lab-grown human spinal cord organoids — miniature organs derived from stem cells — Northwestern scientists have modeled different types of spinal cord injuries and tested a promising new regenerative therapy.
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Long COVID Brain Fog Far More Common in US than India, Other Nations
Patients with long COVID-19 in the U.S. report far higher rates of brain fog, depression and cognitive symptoms than patients in countries such as India and Nigeria, according to a large international study led by Northwestern Medicine.
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Targeting Key Proteins in Fight Against ALS
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein accumulation in neurodegenerative diseases, according to a study published in Nature Communications.
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How Inflammation Fuels Blood Cancer Risk
A Northwestern Medicine-led study published in The Journal of Clinical Investigation has uncovered why older individuals with specific genetic mutations face a heightened risk of developing serious blood cancers.
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New Treatment Directions for Rare Brain Disorder
A Northwestern Medicine study has uncovered a promising new therapeutic approach for a rare genetic brain disorder, according to findings published in Nature Communications.
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Post-Stroke Injection Protects the Brain in Preclinical Study
Northwestern University scientists have developed an injectable regenerative nanomaterial that helps protect the brain during the vulnerable window after a patient suffers a stroke.
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Investigating HIV’s Hidden Immune Evasion Strategy
A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding detection.
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Tanning Beds Triple Melanoma Risk, Potentially Causing Broad DNA Damage
Tanning bed use is tied to almost a threefold increase in melanoma risk, and for the first time, scientists have shown how these devices cause melanoma-linked DNA damage across nearly the entire skin surface, according to a recent study.
