Category: Disease Discoveries
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Bioinformatic Computational Tool Analyzes Tissue Samples to Discern Disease
A novel integrative computational technique allowed scientists to classify disease conditions at the molecular level using epigenomic data sets.
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Inflammation Protection May Be Critical to Treating MS
Prolonging a cellular defense response to inflammation could help regenerate the protective coating of axons that is degraded in diseases such as multiple sclerosis, according to a recent study.
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Northwestern Scientists Discover Potential Therapeutic Target for Glioblastoma
Northwestern Medicine investigators have discovered that inhibiting tumor-associated myeloid cells ability to produce specialized metabolites called polyamines may improve the effectiveness of treatments for glioblastoma.
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Antibody Bolsters Immune Response to Glioblastoma
Northwestern Medicine scientists have engineered a novel antibody that revitalizes immune cell activity in a deadly brain cancer, according to a recent study.
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Northwestern Medicine Scientists Track COVID-19 Variants
Since March 2020, a team of Northwestern Medicine scientists have been tracking the evolution of SARS- CoV-2, specifically in the city of Chicago. Their work has been pivotal in understanding how the virus spread to Chicago and what new variants have emerged in the city.
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Conformational Switch Implicated in Neurodegenerative Diseases
Northwestern Medicine scientists have discovered a conformational “switch” that determines the function of the SNARE protein Ykt6, with implications for synucleinopathies, according to a recent study.
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Immune Receptor Linked to Chronic Heart Transplant Rejection
The AXL immune cell receptor has been linked to cardiac allograft vasculopathy, a thickening of vessel walls in transplanted hearts years after implantation, according to a recent study.
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Lurie Children’s Receives $4 Million to Study Lennox-Gastaut Syndrome
Northwestern and Lurie Children’s Hospital investigators have been approved for a $4 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to study Lennox-Gastaut Syndrome.
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Changes in Macrophages Drive Vulnerability to Lung Infections
An age-related accumulation of a signaling molecule may be one culprit behind older adults’ vulnerability to viral pneumonias, according to a recent study.
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New Spherical Nucleic Acid ‘Drug’ Kills Tumor Cells in Humans With Glioblastoma
An experimental spherical nucleic acid drug developed by Northwestern scientists was able to penetrate the blood-brain barrier and trigger the death of glioblastoma cells.
