Category: Disease Discoveries
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New Version of COVID-19 Vaccine Controls Breakthrough Infections Better
A new combination COVID-19 vaccine improved protection against breakthrough infections in mice, according to a recent Northwestern Medicine study.
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Hypoxic Inflammation Blunts Repair After Heart Attack
Inefficient cardiac repair after heart attacks is partially driven by a maladapted response to a low oxygen environment by immune cells, according to a study published in the Journal of Experimental Medicine.
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Study Identifies Genetic Variants Associated with COVID-19 Severity
In collaboration with Northwestern Medicine investigators, an international multi-center study has identified genetic factors associated with SARS-CoV-2 infection and COVID-19 severity.
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Gene Implicated in Poor Skin Cancer Therapy Outcomes
Losing a check on T-cell activation in cutaneous T-cell lymphoma cells is associated with poor outcomes, according to a study published in Blood.
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Nanoparticles Could Boost Immunotherapy
Enhancing the anti-cancer function of natural killer cells with nanoparticles could unlock their therapeutic potential, according to a Northwestern Medicine study.
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CARDIA Study Enters 35th Year
Thirty-five years since it was started, the Coronary Artery Risk Development in Young Adults study, or CARDIA, has become a premier source for the determinants, mechanism and outcomes of cardiovascular disease and manifestations of aging.
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Muscle’s Smallest Building Blocks Disappear After Stroke
In a new study, Northwestern University and Shirley Ryan AbilityLab researchers have discovered that, in an attempt to adapt to this impairment, muscles actually lose sarcomeres — their smallest, most basic building blocks.
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Study Explores Possible Therapeutic Target for SARS-CoV-2
Inhibiting a specific protein complex in SARS-CoV-2, the virus that causes COVID-19, may be a promising therapeutic target for treating the disease, according to a Northwestern Medicine study.
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Immunosuppression Drug Could Reduce Chemotherapy Resistance
A drug currently used to prevent organ rejection in transplants could also reduce chemotherapy resistance in glioblastoma, according to a Northwestern Medicine study.
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Modern Malady
One of the biggest diseases of the modern era is a pernicious cluster of risk factors called metabolic syndrome, and Northwestern scientists across disciplines are looking for new ways to understand, target, treat, and even prevent this syndrome, with the hopes of ultimately creating a much healthier nation.
