Category: Disease Discoveries
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Genetic Variants in Epilepsy Gene Identified
Investigators have discovered a new method to determine whether individual genetic variants in the epilepsy-associated gene SZT2 cause the neurodevelopmental disorder, according to a Northwestern Medicine study.
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Genome-wide Intricacies of Cancer Inhibitor Untangled
A newly discovered inhibitor of a common cancer-causing protein operates selectively, reducing expression of genes that fuel rampant cell proliferation, and altering the epigenome, according to a recent study.
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Study Shows Cell Membrane-Bound Enzyme is Essential for COVID-19 Infection
The membrane-bound form of the ACE2 protein is the essential receptor for enabling COVID-19 infectivity, according to a Northwestern Medicine study.
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Study Identifies New Therapeutic Target for Most Common Type of Pancreatic Cancer
Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.
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New Regulator of Therapy Resistance in Prostate Cancer
Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.
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New Regulator of Prostate Cancer Metastasis Discovered
A transcription factor associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis.
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New Tool to Create Hearing Cells Lost in Aging
Northwestern Medicine scientists have discovered a master gene that programs ear hair cells’ development, overcoming a major hurdle towards restoring hearing.
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Almost Half of Heart Failure Patients Have Uncontrolled Hypertension and Diabetes
A new Northwestern Medicine study has found almost half of U.S. adults with heart failure have poorly controlled hypertension and diabetes.
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Regulator of Cancer ‘Stemness’ Discovered
The protein FOXK2 promotes survival of cancer stem cells in ovarian cancer, according to a Northwestern Medicine study.
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Expanding HIV Science
In this feature story, Northwestern scientists share their work at the forefront of HIV research, pioneering new strategies to investigate, treat, and work towards a cure for the disease.
