Category: Disease Discoveries
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Circadian Rhythm Causes Metabolic Dysfunction in Fat Cells
Northwestern Medicine scientists have discovered how disruptions in circadian rhythm impair metabolic function in fat cells, providing new insights into the molecular mechanisms that cause obesity and metabolic disease, according to a recent study published in Nature Metabolism.
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As Superagers Age, They Make at Least Twice as Many New Neurons as Their Peers
New research shows that the brains of “SuperAgers” continue to generate new neurons in the hippocampus at levels far higher than typical older adults, and even much younger individuals.
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Study Reveals Why Some Immune Disorders Trigger Severe Food Allergies — and Others Don’t
A new study has shed light on why patients with certain rare immune disorders develop severe, food‑triggered allergic reactions while others with similar diagnoses do not.
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Targeting STING Pathway Triggers Cytotoxic and Immune Responses Against Meningioma
Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Communications.
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HPV Cancer Vaccine Slows Tumor Growth, Extends Survival in Preclinical Model
Northwestern scientists have discovered that systematically changing the orientation and placement of a single cancer-targeting peptide can lead to drug formulations that supercharge the immune system’s ability to attack tumors.
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Paralysis Treatment Heals Lab-Grown Human Spinal Cord Organoids
Using lab-grown human spinal cord organoids — miniature organs derived from stem cells — Northwestern scientists have modeled different types of spinal cord injuries and tested a promising new regenerative therapy.
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Long COVID Brain Fog Far More Common in US than India, Other Nations
Patients with long COVID-19 in the U.S. report far higher rates of brain fog, depression and cognitive symptoms than patients in countries such as India and Nigeria, according to a large international study led by Northwestern Medicine.
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Targeting Key Proteins in Fight Against ALS
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein accumulation in neurodegenerative diseases, according to a study published in Nature Communications.
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How Inflammation Fuels Blood Cancer Risk
A Northwestern Medicine-led study published in The Journal of Clinical Investigation has uncovered why older individuals with specific genetic mutations face a heightened risk of developing serious blood cancers.
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New Treatment Directions for Rare Brain Disorder
A Northwestern Medicine study has uncovered a promising new therapeutic approach for a rare genetic brain disorder, according to findings published in Nature Communications.
