Category: Disease Discoveries
-
Pioneering New Techniques in the Fight Against Alzheimer’s Disease
More than seven million Americans aged 65 years and older currently live with Alzheimer’s disease, according to recent estimates from the Alzheimer’s Association. As the prevalence of the disease increases, so does the need for research that identifies underlying mechanisms of disease to enhance the effectiveness of current therapies and inform new therapeutic strategies.
-
New Biomarkers Needed to Evaluate Heart Failure Risk Post-Pregnancy
Biomarkers used to predict heart failure risk in the general population may be ineffective for assessing risk after pregnancies complicated by hypertension or diabetes, according to a study published in JAMA Cardiology.
-
The Antibiotic That Takes the Bite Out of Lyme
A new Northwestern study shows piperacillin, an antibiotic, effectively cured mice of Lyme disease at a dose 100 times smaller than the effective dose of doxycycline, the current gold-standard treatment.
-
Post-Treatment Lyme Disease Syndrome May Be Driven by Remnants of Infection
A new Northwestern study may explain why the body may continue to respond to an invisible threat long after bacterial death in Lyme disease.
-
Novel Mechanisms Help Lethal Bacteria Recognize and Infect Cells
Scientists led by Karla Satchell, PhD, have discovered previously unknown molecular mechanisms that help a type of foodborne bacteria called Vibrio vulnificus recognize host cells and initiate infection, according to a recent study published in Science Advances.
-
Novel Mechanisms Regulate Immune Response to Cancer and Infection
Northwestern Medicine investigators have discovered new intracellular mechanisms that help specialized immune cells adapt and respond to disease and acute inflammation, findings that may inform the development of targeted therapies for cancer and tissue injury, according to a recent study published in the Journal of Clinical Investigation.
-
Common Genetic Variants Help Determine Heart Failure Risk, Study Finds
Screening for common genetic variants in addition to rare genetic variants can help improve patient risk stratification for heart failure, according to a recent Northwestern Medicine study published in Nature Genetics.
-
Enzyme Drives Treatment Resistance in Ovarian Cancer
Northwestern Medicine scientists have identified a key driver of chemotherapy resistance in advanced ovarian cancer, according to a study published in the Journal of Clinical Investigation.
-
Many Young Adults Have High Long-term Risk for Cardiovascular Disease, Study Finds
A recent Northwestern Medicine study published in JAMA has found that one in seven U.S. adults between the ages of 30 and 59 years have a high 30-year risk for cardiovascular disease.
-
Protein Implicated as Driver of Lung Cancer
Northwestern Medicine scientists have uncovered how a testis-specific protein contributes to tumor growth and progression when it is mis-expressed in lung cancer, according to a study published in Science Advances.
