Year: 2021
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Inhibiting Protein Degradation May Prevent Cocaine-Induced Reward Behaviors
Northwestern Medicine investigators have discovered that inhibiting a specific autophagy protein found in dopaminergic neurons may prevent reward-related behaviors induced by cocaine misuse.
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Identifying Therapeutic Targets for B-cell Acute Lymphoblastic Leukemia
Northwestern Medicine investigators have identified a protein kinase called DYRK1A and its downstream substrates as potential therapeutic targets for treating pediatric patients with B-cell acute lymphoblastic leukemia.
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Antibody Drug Improves Survival for Aggressive Breast Cancer
A new antibody drug demonstrated similar efficacy to currently available therapies to treat advanced ERBB2-positive breast cancer, according to a recent clinical trial.
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Mother’s Heart Health in Pregnancy Impacts Child’s Heart Health in Adolescence
A mother’s heart health while she is pregnant may have a significant impact on her child’s cardiovascular health in early adolescence, according to a new study from Northwestern and Lurie Children’s Hospital.
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Second-year Medical Student Reflects on Music, Research and Volunteer Opportunities
Second-year medical student and musician Mallika Patel reflects on collaborative research efforts with Feinberg faculty and her experience volunteering for the COVID-19 Med Supply Drive’s Illinois chapter.
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Novel Injectable Therapy Shows Promise in Treating Crohn’s Disease
A team of Northwestern investigators has demonstrated that injection of anti-inflammatory peptide amphiphiles into intestinal lesions can reduce inflammation in an animal model of Crohn’s disease.
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Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
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Uncovering How Protein Complexes Impact Gene Expression
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
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New Anti-Obesity Medication Almost Twice as Effective as Most Currently Approved Weight-Loss Drugs
A new anti-obesity medication is almost twice as effective at helping individuals lose weight than current weight-loss drugs, according to a Northwestern Medicine study.
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Why Black Men’s Prostate Cancer May be More Responsive to Immunotherapy
A new Northwestern Medicine study has discovered why Black men die more often of prostate cancer yet also have greater survival benefits from immunotherapy treatments.
