Mutations in a gene called DBR1 may increase patients’ susceptibility to brain infection, according to a study published in Cell.
Scientists discovered the regulatory role of the enzyme CDK5 in an aggressive form of brain cancer and successfully halted tumor growth by inhibiting it.
In new clinical trials, a gene therapy for a serious blood disorder called beta-thalassemia significantly improved outcomes among patients, without serious side effects.
Scientists found more than 100 possible cancer-causing mutations and defective alleles in a large-scale genetic analysis of pediatric cancers that was co-authored by Elizabeth Perlman, MD, and published in Nature.
Scientists have developed software that can forecast the survival of patients diagnosed with glioma that is more accurate than physicians’ predictions.
Northwestern Medicine scientists usher in a new era of genetic research. Learn how our investigators are using CRISPR technology to isolate mutations that cause neurological diseases and to understand how individual genes can damage or protect cells.
Northwestern Medicine scientists have discovered mutations that cause improper drainage and a buildup of ocular pressure leading to glaucoma, suggesting a path towards future treatments.
A team from the academic and clinical arms of
Northwestern Medicine has been assembled to study patient DNA and create customized therapies for Parkinson’s, Epilepsy, and ALS in a model called Personalized Neurology.
Scientists are one step closer to a stem cell treatment for muscular dystrophy after Northwestern Medicine investigators demonstrated improvements in muscle tissue differentiation in stem cells.
Scientists reduced blood clotting in mice with a blood disease called myeloproliferative neoplasm by inhibiting expression of a gene.