Recently published research in Human Molecular Genetics shows that removing too much of the enzyme HDAC3 has a toxic effect on the nervous system. The expression of this enzyme is inhibited by drugs being studied as potential treatment options for cancer and neurodegeneration
Browsing: Disease Discoveries
Scientists identified a new protein that plays a key role in reprogramming cancer cells to migrate and invade other organs. When that protein is removed from cancer cells in mice models of the disease, the ability of the cells to metastasize to the lungs is dramatically decreased.
Findings published by Northwestern Medicine scientists in Molecular Cell suggest that the upregulation of protein WDR5 may be crucial in prostate cancer development.
Published in Nature Neuroscience, the findings offer a promising route for developing new treatment options in Parkinson’s disease.
Kamonwan Pear Fish, a PhD/MPH student, uses mouse models to study how a viral protein from the Epstein Barr Virus can disrupt cell function and accelerate tumor growth.
Despite advances in neurosurgical techniques and radiation oncology, malignant brain tumors are the fourth most common cancer death in the United States. A recent publication by Northwestern Medicine scientists has revealed a potentially novel treatment option.
Circadian Science Advances Speed Up Importance Of Timing In Medicine
The experimental drug prolonged the lifespan in a mouse model of accelerated aging by inhibiting a protein that plays a key role in the process.
Published in Science Translational Medicine, new high-impact research findings from scientists at Northwestern Medicine could produce novel approaches to treat the tissue scarring known as fibrosis.
Published in mBio, the findings offer the first evidence that seminal plasma may have a direct role in promoting the transmission of a sexually transmitted infection.