Category: Disease Discoveries
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Axonal Defects Linked to Rare Form of Parkinson’s Disease
A genetic mutation linked to Parkinson’s disease produced abnormalities in a subset of nerve cells, offering a clue about the disease’s causes, according to a new study published in the Proceedings of the National Academy of Sciences.
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Years of Opioid Use Do Not Improve Chronic Pain, Study Finds
Taking opioids for years does not seem to improve pain and functioning in people with chronic back pain, according to a new Northwestern University study.
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Understanding How Immune Cells Can Drive Blindness
A Northwestern Medicine study published in the Journal of Clinical Investigation has identified a previously unrecognized population of immune cells that appears to fuel harmful blood vessel growth in multiple blinding eye diseases.
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Investigating How Brain Tumors Evolve
A new study published in Nature sheds light on how two major types of brain tumors progress over time, offering critical biological insights that could guide treatment decisions.
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Ovaries Remain Biologically Active Even Decades After Menopause
Scientists have found that in the decades well past menopause, the ovary remains biologically active and continues to remodel with age, showing increased inflammation and changes in tissue structure.
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New Tumor State Helps Identify High-Risk Small-Cell Lung Cancer
Northwestern Medicine scientists have identified a stem-like state in small-cell lung cancer that identifies a group of patients with exceptionally poor outcomes following chemoimmunotherapy, according to a study published in Cell Reports Medicine.
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For People With a Rare Skin Disorder, High Allergy Risk Adds Another Burden
Most study participants reported at least one allergic disorder in addition to lamellar ichthyosis, a rare skin condition that can cause painful blisters and scaly skin.
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Understanding the Link Between Genetic Risk and Brain Communication Disorders
A new Northwestern Medicine study suggests a major psychiatric risk gene remains important well into adulthood and may influence brain communication, according to a study published in the Proceedings of the National Academy of Sciences.
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Investigating Tumor Growth After Immunotherapy
A new Northwestern Medicine study has uncovered a biological mechanism that may explain why a subset of tumors unexpectedly grows at an accelerated rate after being treated with certain immunotherapies, according to findings published in Cancer Discovery.
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Experimental Drug May Disrupt Immune Circuits in Pneumonia
A drug that blocks calcium release-activated calcium channels may help interrupt harmful immune cell interactions that drive severe viral pneumonia, according to a new study published in The Journal of Clinical Investigation.
