Tag: Research
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Novel ‘Feeding’ Mechanism Promotes Glioblastoma Treatment Resistance
Northwestern Medicine investigators have discovered that specialized immune cells within the glioblastoma tumor microenvironment use a unique “feeding” mechanism that promotes tumor growth and treatment resistance, according to findings published in the journal Cell Metabolism.
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2023 Year in Review
Feinberg experienced a year of outstanding growth, scientific achievement, and collaboration in 2023, from honors and awards to unprecedented research discoveries.
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Localized Genetic Mutations May Serve as Biomarker for Wide Range of Cancers
Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification and treatment, according to findings published in Proceedings of the National Academy of Sciences.
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Study Discovers Novel Biomarker for Vascular Aging and Neurodegeneration
Decreased activity of a specific signaling pathway in the brain vessels of aging mice and humans was linked to a decline in vascular function and subsequent neurodegeneration, according to a recent Northwestern Medicine study published in the Journal of Clinical Investigation.
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Semaglutide Trials Show Improvements in Cardiovascular Health, Quality of Life
Two years after the FDA’s approval of semaglutide for chronic weight management, Northwestern Medicine scientists remain at the forefront of investigating the drug’s potential in helping patients who are overweight or have obesity who also have other preexisting health conditions.
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Exploring How Poxviruses Dismantle Antiviral Responses
Northwestern Medicine investigators led by Derek Walsh, PhD, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, according to findings published in Nature Communications.
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Top 3 Breakthroughs Podcasts of 2023
The Breakthroughs podcast released 19 episodes in 2023 on topics ranging from implementation science and ChatGPT to new insights in dopamine and AI in healthcare. The top three most downloaded episodes this year were on varying topics including exercise and Parkinson’s disease, food allergies and recent discoveries about mitochondria.
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Developing Deep Learning Models to Understand the Human Genome
Northwestern Medicine scientists have developed a deep learning algorithm accelerating research around diseases and disorders that occur when the process of DNA transcription goes awry.
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Krainc, Kelley Elected to National Academy of Inventors
Dimitri Krainc, MD, PhD, the Aaron Montgomery Ward Professor and chair of the Davee Department of Neurology and director of the Simpson Querrey Center for Neurogenetics, has been elected to the National Academy of Inventors.
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Bone Transcription Factor Controls Nervous System Gene Expression
An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, according to a Northwestern Medicine study published in Neuron.
