Tag: Research
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Developing Tools to Explore DNA Methylation
A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.
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Potential Therapeutic Target for Small Cell Lung Cancer Discovered
Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer cells may decrease cancer cell differentiation and tumor growth, according to findings published in Nature Communications.
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Novel Mechanism Supports Antitumor Response and T-cell Survival
A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of Clinical Investigation.
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Probing Deeper to Understand Protein Expression in Neurons
Northwestern Medicine investigators have developed a method to measure protein expression in an individual neuron type, according to a study published in Molecular Psychiatry.
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Novel Biological Mechanism Discovered That Could Lead to New Treatments for Neurological Disorders, Cancers
The lab of Yongchao C. Ma, PhD, has discovered a fundamental biological mechanism that could lead to new treatments for neurological diseases, such as spinal muscular atrophy (SMA) and autism, as well as different cancers.
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Tracking the Evolution of COVID-19
Scientists have developed a machine-learning approach to track the evolution of the COVID-19 virus and potentially others, according to a study published in the Proceedings of the National Academy of Sciences.
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A Day in the Life: MSTP Student Juliana Feng
Meet Juliana Feng, a student at Feinberg School of Medicine in the first year of her PhD program. She’s a student in the Medical Scientist Training Program (MSTP). She has completed two years of medical school and is now in the graduate school portion of her program.
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Implantable Sensor Enables Patients and Physicians to Monitor Bladder Function
Northwestern scientists have developed a new soft, flexible, battery-free implant that allows patients and physicians to monitor bladder fullness in real time.
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Novel Role for Metabolites in Cellular Metabolism Discovered
Investigators led by Issam Ben-Sahra, PhD, have discovered how cellular metabolism fluctuates in response to changes in levels of pyrimidines, metabolites used by cells to make DNA and RNA, according to a recent study published in Science.
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Predicting Infection Risk in Childhood Cancer
A model can accurately predict the risk of bloodstream infections in a subset of children with cancer, according to a study published in the Journal of Clinical Oncology.
