A new study suggests that a dysfunction in neurons’ synapses leads to deficits in dopamine and precedes the neurodegeneration previously thought to cause Parkinson’s disease.
An experimental drug targeting a genetic variant linked to Parkinson’s disease had no effect on patients, according to the results of a new clinical trial published in The Lancet Neurology.
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a renewed five-year $10.8 million Specialized Program of Research Excellence (SPORE) grant from the National Cancer Institute for the Lurie Cancer Center to advance translational research and improve outcomes for patients with brain cancer.
A new Northwestern University-led study published in Nature Neuroscience has discovered that dopamine neurons are more diverse than previously thought, opening new research directions for further understanding and potentially even treating Parkinson’s disease.
Northwestern Medicine scientists have uncovered a new mechanism by which mutations in a specific gene contribute to familial forms of Parkinson’s disease, which opens an avenue for new therapeutics.
A recent Northwestern Medicine study has revealed that the brain’s temporal pole has critical functions in word comprehension, face recognition and the regulation of behavior.
A team led by Northwestern Medicine investigators have discovered novel cellular mechanisms that lead to chemotherapy resistance in recurrent glioblastoma, according to findings published in Science Advances.
Northwestern Medicine scientists have discovered how octopamine, the major “fight-or-flight” neurotransmitter in invertebrates, communicates with other cells to prevent cell death in mammalian brains, according to a study published in the Proceedings of the National Academy of Sciences.
Repeat radiation therapy combined with monoclonal antibody treatment extended progression-free survival in patients with recurrent glioblastoma, according to a recent clinical trial published in the Journal of Clinical Oncology.
Sandra Weintraub, PhD, professor of Psychiatry and Behavioral Sciences in the Division of Psychology and associate director of the Northwestern Alzheimer’s Disease Research Center in the Mesulam Center for Cognitive Neurology and Alzheimer’s Disease, was recently appointed to the Illinois Supreme Court Commission on Elder Law.