Tag: Neurology
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Exploring Intracellular Communication to Understand Neurodegeneration
Investigators have uncovered a new communication pathway between mitochondria and RNA granules that may improve the understanding of how the toxic buildup of the TDP-43 protein leads to the development of certain neurodegenerative diseases, according to a recent study published in Nature Communications.
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Skin-Resident Immune Cells Drive Neuropathic Pain in Diabetes
In experimental models of diabetes, Northwestern Medicine scientists have discovered that a specialized group of skin-resident immune cells drive neuropathic pain through sex-dependent signaling pathways, according to a recent study published in The Journal of Clinical Investigation.
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ALS is Driven by a Domino‑Like Chain Reaction That Begins in Nerve Cells
A new Northwestern Medicine study provides evidence that ALS unfolds through a domino‑like sequence of events that begins with an early breakdown inside motor neurons and is followed by a damaging inflammatory response.
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Targeting Novel Long Non-Coding RNA May Improve Glioblastoma Treatment
Scientists have discovered that increased expression of a novel long non-coding RNA drives glioblastoma cell growth alongside a genetic amplification found in more than half of glioblastoma tumors, according to a Northwestern Medicine study published in Nature Cell Biology.
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Uncovering Cellular Drivers of Increased Brain Signal Activity
Northwestern Medicine scientists have discovered new insights into how high gamma activity, a widely studied brain signal, is generated, findings that can impact how past and future neurological studies using this signal are interpreted, according to a recent study published in Nature.
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Imagination is More Than Sensory Replay
A new Northwestern University study suggests that higher‑level brain systems that interpret and organize perception may play a central role in imagination in addition to sensory systems.
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FDA-Approved Compound Promotes Neuroprotective Effects in Parkinson’s Disease
Northwestern Medicine scientists have discovered an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson’s disease, according to a recent study published in The Journal of Clinical Investigation.
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As Superagers Age, They Make at Least Twice as Many New Neurons as Their Peers
New research shows that the brains of “SuperAgers” continue to generate new neurons in the hippocampus at levels far higher than typical older adults, and even much younger individuals.
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Living ‘Mini Brains’ Meet Next-Generation Bioelectronics
A team led by Northwestern University and Shirley Ryan AbilityLab scientists have developed a new technology that can eavesdrop on the hidden electrical dialogues unfolding inside miniature, lab-grown human brain-like tissues.
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Experimental Stroke Drug Slows Bleeding but Doesn’t Improve Recovery
A global clinical trial has found that recombinant factor VIIa, a drug designed to rapidly slow bleeding in the brain after a hemorrhagic stroke, does not improve long‑term recovery for patients, according to a study published in The Lancet
