Tag: Neurology and Neuroscience
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Next-Gen Sequencing
Northwestern’s investment in next-generation sequencing is leading to unprecedented avenues of discovery.
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Conformational Switch Implicated in Neurodegenerative Diseases
Northwestern Medicine scientists have discovered a conformational “switch” that determines the function of the SNARE protein Ykt6, with implications for synucleinopathies, according to a recent study.
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Lurie Children’s Receives $4 Million to Study Lennox-Gastaut Syndrome
Northwestern and Lurie Children’s Hospital investigators have been approved for a $4 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to study Lennox-Gastaut Syndrome.
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New Spherical Nucleic Acid ‘Drug’ Kills Tumor Cells in Humans With Glioblastoma
An experimental spherical nucleic acid drug developed by Northwestern scientists was able to penetrate the blood-brain barrier and trigger the death of glioblastoma cells.
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New Genetic Cause of Dystonia Revealed
Northwestern Medicine scientists discovered mutations in a scaffolding protein contributes to dystonia, an incurable movement disorder.
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Blocking Cell Division in Glioblastoma
Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
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Untangling Cellular Changes in Pediatric Epilepsy
For the first time, Northwestern Medicine scientists have characterized how a genetic mutation associated with pediatric epilepsy affects neuron activity.
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Plotting the Neural Circuitry of Appetite Suppression
Northwestern Medicine scientists have uncovered a neural circuit that drives fear-induced suppression of feeding, according to a study published in Neuron.
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‘Logic Circuit’ in Cochlear Neurodevelopment Identified
For the first time, Northwestern Medicine scientists have uncovered the complex logic that determines how cochlear cells are connected to the brain during neurodevelopment, according to a recent study.
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New Therapeutic Prospect for ALS
An experimental drug called ezogabine reduced spinal neuron excitability in patients with ALS, according to a recent study.
