Tag: Medicine
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Study Uncovers Novel Mechanisms Behind Food Allergies
A recent Northwestern Medicine study sheds light on the mechanisms of a specific protein that is necessary for the production of IgA antibodies in the gut in response to food allergens, according to findings published in the journal Mucosal Immunology.
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Release of Inhibitory Pathways May Promote Immune Response to HIV
Recent work from the laboratory of Elena Martinelli, PhD, MPH, has discovered how inhibiting an immune cell singling pathway in a model of HIV-1 infection may promote immune responses and decrease viral persistence in conjunction with antiretroviral therapy.
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Treating Skin Cancer Without Risking Transplanted Kidneys in Organ Recipients
Specific immunosuppressants and immunotherapy are not enough to prevent organ rejection in patients undergoing skin cancer treatment who have also received a kidney transplant, according to a clinical trial published in the Journal of Clinical Oncology.
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Cellular Therapy Increases Survival in Recurring B-cell Lymphoma
A two-year follow-up clinical trial found that a personalized cellular therapy treatment for relapsed or refractory B-cell lymphoma demonstrated high safety and improved overall survival in patients, according to findings published in Blood.
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Engineered Heart Cells May Improve Understanding of Atrial Fibrillation
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
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Transcription Factors Influence Insulin-Producing Beta Cells
A recent study from the laboratory of Joseph Bass, MD, PhD, has revealed how transcription factors within individual cells influence the identity and function of insulin-producing beta cells in the pancreas, according to findings published in Cell Metabolism.
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As Patients Live Longer, New Criteria Needed for Prostate Cancer Trials
A lack of cancer progression could be used as a surrogate for overall survival in newly metastatic prostate cancer clinical trials, according to a new meta-analysis published in the Journal of Clinical Oncology.
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Novel Protein Interactions May Serve as Biomarker for Heart Disease
Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.
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Defining Rheumatoid Arthritis Subtypes May Improve Treatments
By profiling the inflammatory cells types in joint tissue biopsy samples, scientists have characterized six subtypes of rheumatoid arthritis, an approach that could help physicians tailor more effective treatment strategies for patients based on disease type, according to findings published in Nature.
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New Brain-Like Transistor Mimics Human Intelligence
Taking inspiration from the human brain, scientists have developed a new synaptic transistor capable of higher-level thinking, according to results published in the journal Nature.
