
A common diabetes medication does not help people with peripheral artery disease (PAD) walk farther, according to results from a major U.S. clinical trial published in JAMA.

Scientists have discovered previously unknown cellular mechanisms that regulate the production of renin, an essential enzyme in the kidney, findings that could improve the understanding of how the kidney regulates its function and how chronic kidney disease develops, according to a recent study published in Cell.

A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding detection.

Increased esophageal hypervigilance and anxiety were associated with worse post-treatment symptoms and poor quality of life in patients with achalasia, a rare esophageal motility disorder, according to a recent Northwestern Medicine study.

Northwestern Medicine scientists, along with collaborators from the Washington University School of Medicine, have developed a noninvasive nanomedicine approach that may improve the treatment of glioblastoma, according to a recent study published in the Proceedings of the National Academy of Sciences.

While menopausal hormone therapy increased cardiovascular disease risk in postmenopausal women older than 70 years with vasomotor symptoms, hormone therapy did not significantly affect cardiovascular disease risk in younger postmenopausal women, according to a recent study published in JAMA Internal Medicine.

Northwestern scientists have discovered how IgA antibodies are produced through unexpected cellular pathways, findings that may help inform the design of more effective vaccines to prevent infections, according to a recent study.

In a new study of nearly 1,000 consecutive patients treated for lung cancer at Northwestern Medicine, investigators discovered only 35 percent would have qualified for screening according to the U.S. Preventive Services Task Force (USPSTF) screening criteria.

Northwestern Medicine scientists have uncovered new insights into how the PAI-1 protein contributes to cardiovascular aging and how inhibiting PAI-1 may be a promising therapeutic approach for mitigating cardiovascular disease, according to recent findings published in The Journal of Clinical Investigation.

A recent Northwestern Medicine study has identified novel neural circuits modulated by the diabetes and obesity-management drugs semaglutide and tirzepatide that help suppress appetite, according to findings published in The Journal of Clinical Investigation.