Tag: Medicine
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Potential Therapeutic Target for Ischemic Acute Kidney Injury Discovered
Investigators led by Pinelopi Kapitsinou, MD, have discovered that inhibiting the hypoxia-driven MCT4 protein in kidney endothelial cells may halt the progression of ischemic acute kidney injury to chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation.
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Improving the Treatment of Valvular Heart Diseases
Transcatheter heart valve replacement significantly improved outcomes in patients with severe valvular heart diseases compared to standard care alone, according to two recent clinical trials published in the New England Journal of Medicine.
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Combination Therapy Does Not Extend Survival in Glioblastoma
Patients with a subtype of glioblastoma who received a combination treatment of a PARP inhibitor and standard chemotherapy did not demonstrate improved survival compared to chemotherapy and placebo, according to a recent clinical trial published in JAMA Oncology.
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Immunotherapy Shows Potential to Treat Deadly Thyroid Cancer
A type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results of a clinical trial published in JAMA Oncology.
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Scientists Develop Approach to Accurately Predict Pneumonia Outcomes
By applying a sophisticated machine-learning approach to electronic health records of patients with pneumonia, investigators at Northwestern University have uncovered five distinct clinical states in pneumonia.
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Novel Blood Test Predicts Risk of Severe Lung Disease
Northwestern Medicine investigators have created a novel blood test that identifies adults who may be at increased risk of developing severe respiratory illnesses, according to a recent study published in the American Journal of Respiratory and Critical Care Medicine.
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Targeting T-cell Lipid Metabolism May Improve Cancer Immunotherapy
Investigators have discovered that targeting specific mechanisms linked to lipid metabolism in immune cells within tumors may improve response to current and future cancer immunotherapies, according to a recent study published in the journal Immunity.
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Virtual Palliative Care Outcomes Similar to In-Person, Study Finds
Patients receiving palliative care via telehealth report similar quality-of-life scores compared to those who had in-person care, according to a multicenter clinical trial recently published in JAMA.
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Understanding the Molecular Players in Eye Inflammation
Northwestern Medicine investigators have shed new light on how white blood cells in the retina function during inflammation and possibly during retinal vascular diseases with inflammatory components like diabetic retinopathy, according to a study recently published in the Journal of Clinical Investigation.
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Combination Treatment Improves Progression-Free Survival in Advanced Prostate Cancer with Genetic Mutations
A combination therapy improved progression-free survival in patients with metastatic castration-resistant prostate cancer with genetic mutations compared to either therapy alone or sequentially, according to results from a Northwestern Medicine-led clinical trial.
