Tag: Medicine
-
‘Leaky’ Muscle Fibers Drive Immune Response in Muscular Dystrophy
A Northwestern Medicine study has uncovered how chronic defects in muscle membrane repair can fuel harmful inflammation, according to the study published in JCI Insight.
-
Immune Receptor Plays Dual Role in Promoting T-cell Exhaustion in Cancer
A new Northwestern Medicine study has uncovered how a key immunoregulatory receptor plays an unexpected dual role in promoting T-cell exhaustion during chronic infection and cancer, according to findings published in the Proceedings of the National Academy of Sciences.
-
Immunotherapy Shows Long-Term Promise in Aggressive Lymphoma
A leading-edge immunotherapy may extend survival for patients with one of the most aggressive forms of blood cancer, according to newly published five-year results from a major clinical trial in the journal Blood.
-
New GLP-1 Drug Promotes Weight Loss in Obesity
A new strategy for delivering GLP-1 drugs to patients with obesity or who were overweight resulted in up to an 11 percent reduction in body weight after 36 weeks, according to a randomized phase II clinical trial published in Nature Medicine.
-
Cryoprobe Improves Diagnostic Accuracy and Safety in Lung Biopsies
Transbronchial lung biopsy procedures performed with a 1.1 millimeter cryoprobe demonstrated higher diagnostic accuracy and safety than two-millimeter forceps in patients with lung nodules or masses and lung transplant, according to a recent randomized trial published in JAMA.
-
Lymphatic Dysfunction Drives Heart Valve Disease
Dysfunction in the lymphatic system has been identified as a hidden driver of life‑threatening heart valve disease in patients with Marfan syndrome, according to a new Northwestern Medicine study published in The Journal of Clinical Investigation.
-
Immune Cell Circuit Restores Barrier Function in IBD
Scientists have discovered a new communication circuit between immune cells in the intestines, a potential therapeutic target to improve inflammatory bowel disease outcomes, according to a recent study published in the Proceedings of the National Academy of Sciences.
-
Expanding the Evidence for Behavioral Interventions in Gastroenterology
The Division of Gastroenterology and Hepatology at Feinberg has a distinct strength in understanding how behavior and lifestyle influence gastrointestinal (GI) health. The Division conducts research aimed at improving treatments for disorders of the digestive tract and related organs.
-
Bacteria ‘Rewire’ Epithelial Cells and Drive Disease in the Gut
A bacterial pathogen that causes colitis and colorectal cancer creates a nutrient-rich niche and “rewires” epithelial cell signaling in the inflamed gut, which promotes bacterial colonization and disease, mechanisms that may be promising therapeutic targets, according to a recent study published in the journal Cell.
-
Hormone Impacts Red Blood Cell Production in Anemia
Northwestern Medicine scientists have discovered that the hormone FGF23 reduces the production of red blood cells and may contribute to the development of anemia of chronic kidney disease, according to a recent study published in Blood.
