Targeting internal proteins instead of spike proteins may be a promising strategy for monoclonal antibody therapy to combat SARS-CoV-2, the virus that causes COVID-19.
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Browsing: Infectious Diseases
Northwestern Medicine investigators continue to investigate the impact of the COVID-19 pandemic, from evaluating repurposed drugs in preventing severe disease to using sentinel surveillance to monitor SARS-CoV-2 transmission rates and studying the prevalence of “long COVID” in pediatric patients.
Therapeutically inhibiting a metabolic regulator in monocytes unexpectedly increased inflammatory signaling, revealing mechanisms that could inform new strategies to treat chronic inflammatory disorders, according to a recent study.
Northwestern Medicine investigators continue to study COVID-19, from comparing mortality rates between SARS-CoV-2 variants to examining the effectiveness of maternal vaccination in protecting infants and combating COVID-19 misinformation on social media.
Northwestern Medicine scientists are expanding the global network of COVID-19 sequencing in regions where there is limited viral genetic information reporting.
The membrane-bound form of the ACE2 protein is the essential receptor for enabling COVID-19 infectivity, according to a Northwestern Medicine study.
New advances in CRISPR gene-editing technology may lead to longer-lasting treatments and new therapeutic strategies for HIV/AIDS.
Northwestern Medicine continues to help advance the understanding of the COVID-19 pandemic and its widespread impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research to highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.
A new publication outlines the structure-function relationships between the first spherical nucleic acid vaccine developed to protect against viral infections, including COVID-19.
Frank Palella, MD, is working towards increasing the lifespan and “healthspan” of people living with HIV through research, education and patient care as director of the new Potocsnak Center for Aging and HIV.