Tag: Cell and Developmental Biology
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Understanding Drivers of Egg Cell Development
Northwestern Medicine scientists have identified how cytoskeletal proteins contribute to the growth of developing eggs in fruit flies, findings which further the understanding of how egg cells form and differentiate themselves from other cells, according to a study published in the Proceedings of the National Academy of Sciences.
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Scientists Uncover Why Some Cells Become Resistant to Cancer Therapies
Scientists have created a new synthetic biology approach to follow tumor cells over time, finding meaningful differences in why a cancer cell dies or survives in response to anti-cancer therapies.
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Study Identifies New Mechanisms Driving Genomic Instability
A recent Northwestern Medicine study has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of biomarkers and targeted therapies for cancer.
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Genetic Mutation Responsible for Rare Neurodevelopmental Disorder Identified
Using zebrafish models, investigators have discovered that MAP4K4 genetic variants cause neurodevelopmental delays and other physical abnormalities, demonstrating a potential therapeutic target for treating the disorder in humans, according to findings published in Science Advances.
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Understanding How Exercise Induces Systemic Metabolic Benefits
Northwestern Medicine scientists have uncovered a mechanism by which exercise activates metabolic benefits in the body, according to a new study published in Cell Metabolism.
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Study Identifies Two Genes Linked to Microcephaly
Northwestern Medicine scientists have identified pathogenic variants in two genes linked to microcephaly and other neurodevelopmental disorders in children, according to a recent study published in Nature Communications.
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Center for Genetic Medicine Announces New Director for Transgenic and Targeted Mutagenesis Laboratory
Styliani (Stella) Markoulaki, PhD, has been named the new director of the Transgenic and Targeted Mutagenesis Laboratory.
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New Therapeutic Approach Could Prevent Injury to Fragile Transplanted Lungs
Investigators identified a molecular “brake” that can reduce the activation of damaging cells known to cause primary graft dysfunction — a leading culprit in lung transplant failure.
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Study Identifies Distinct Roles for Nuclear Lamin Isoforms
A Northwestern Medicine study has uncovered distinct roles of major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics.
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Cytoskeletal Proteins Interact to Form Intracellular Networks
Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form essential cytoskeletal networks within the cell surface.
