Tag: Cardiology
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Understanding Inflammation in the Heart
Inflamed heart muscles can mount immune responses even in the absence of immune cells, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
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Novel Drug May Improve Oxygen Uptake in Hypertrophic Cardiomyopathy
Patients with obstructive hypertrophic cardiomyopathy who received a new drug demonstrated improved oxygen uptake and exercise tolerance, according to a study published in the New England Journal of Medicine.
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Regenerating Damaged Heart Cells
Northwestern Medicine scientists have discovered a way to regenerate damaged heart muscle cells in mice, a development which may provide a new avenue for treating congenital heart defects, according to a study published in the Journal of Clinical Investigation.
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Weight Loss Drug Shows Benefits for Heart Failure
Semaglutide, sold under brand names Ozempic and Wegovy, can help reduce heart failure symptoms and reduce heart failure hospitalizations in patients with obesity, according to a pair of studies published in The Lancet and The New England Journal of Medicine.
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Feinberg Investigators Lead AHA Heart Disease Research Initiative
Feinberg investigators have been selected to lead a $15 million American Heart Association research initiative studying the role of inflammation in heart disease.
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‘Polypills’ Can Help Patients Reduce Heart Disease Risk
Combining multiple heart disease drugs into a single “polypill” can lower bad cholesterol and blood pressure, boost medication adherence, and reduce the risk of cardiovascular disease and death, according to a meta-analysis of recent clinical trials published in Nature Medicine.
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Engineered Heart Cells May Improve Understanding of Atrial Fibrillation
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
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Novel Protein Interactions May Serve as Biomarker for Heart Disease
Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.
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Semaglutide Trials Show Improvements in Cardiovascular Health, Quality of Life
Two years after the FDA’s approval of semaglutide for chronic weight management, Northwestern Medicine scientists remain at the forefront of investigating the drug’s potential in helping patients who are overweight or have obesity who also have other preexisting health conditions.
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Investigating Drug Combinations for Heart Failure
A common diabetes medication may help some patients with treatment-resistant hypertension slightly lower their high blood pressure and lessen their risk of heart failure events such as stroke, according to an analysis of a clinical trial published in Circulation.
