Tag: Cancer
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Drug Demonstrates Poor Efficacy in Advanced Bladder Cancer
An FDA-approved monoclonal antibody drug used to treat advanced bladder cancer demonstrated poor efficacy in a recent clinical trial.
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Mitochondria Could Boost Immunotherapy Effectiveness
Boosting mitochondrial function in a subpopulation of T cells could make cancer immunotherapy more effective, according to a recent study.
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Uncovering the Function of Prostate Cancer Protein
Northwestern Medicine scientists have discovered a mechanism that makes a prostate cancer-causing protein called FOXA1 more resilient, according to a recent study.
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Study Discovers Dual Function of Neutrophils in Cancer Cells
Northwestern Medicine investigators have discovered how a particular type of immune cell exerts a dual function in cancer cells that is contingent on tumor grade.
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Inhibiting SAM Biosynthesis to Slow Tumor Growth
Inhibiting production of a key material produced by the mTOR pathway could slow tumor growth, according to a recent Northwestern Medicine study.
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Protein Variant May Have Potential as Target for Glioblastoma
Inhibiting a novel protein variant within glioma stem cells may be a promising therapeutic approach to treat glioblastoma, according to a recent Northwestern Medicine study.
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Bioinformatic Computational Tool Analyzes Tissue Samples to Discern Disease
A novel integrative computational technique allowed scientists to classify disease conditions at the molecular level using epigenomic data sets.
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Northwestern Scientists Discover Potential Therapeutic Target for Glioblastoma
Northwestern Medicine investigators have discovered that inhibiting tumor-associated myeloid cells ability to produce specialized metabolites called polyamines may improve the effectiveness of treatments for glioblastoma.
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Antibody Bolsters Immune Response to Glioblastoma
Northwestern Medicine scientists have engineered a novel antibody that revitalizes immune cell activity in a deadly brain cancer, according to a recent study.
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New Spherical Nucleic Acid ‘Drug’ Kills Tumor Cells in Humans With Glioblastoma
An experimental spherical nucleic acid drug developed by Northwestern scientists was able to penetrate the blood-brain barrier and trigger the death of glioblastoma cells.
