Tag: Cancer
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Northwestern Scientists Develop New Model for Understanding Uterine Fibroids
Northwestern Medicine scientists have developed a new cellular model of uterine fibroids that stem from a common genetic mutation, which will accelerate further research and treatment development, according to findings published in Nature Communications.
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Shields Receives NCI Cancer Moonshot Scholars Award
Mario Shields, PhD, research assistant professor of Medicine in the Division of Hematology and Oncology and a member of the Lurie Cancer Center, has received the National Cancer Institute’s (NCI) Cancer Moonshot Scholar Award.
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Scientists Uncover Why Some Cells Become Resistant to Cancer Therapies
Scientists have created a new synthetic biology approach to follow tumor cells over time, finding meaningful differences in why a cancer cell dies or survives in response to anti-cancer therapies.
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Study Discovers Novel Region for BRD4 Transcription and Potential Therapeutic Target
Northwestern Medicine investigators have discovered a novel protein region that regulates DNA transcription elongation, suggesting a new therapeutic target for treating cancers and developmental disorders, according to findings published in Molecular Cell.
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Immunotherapy Improves Remission for Relapsed, Refractory Leukemia
A single infusion of CAR T-cell therapy induced complete response or remission in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma, according to a recent clinical trial published in The Lancet.
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Broad-Spectrum Antibiotics Decrease Infection Rates in Pancreas Surgery
Administering broad-spectrum antibiotics before surgery to remove pancreas tumors may decrease the chances of surgical site infection, according to a recent study published in JAMA.
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Study Identifies Mechanisms Driving Immune Cell Recruitment During Inflammation
Northwestern Medicine investigators have discovered a novel mechanism that regulates neutrophil recruitment into tissue during inflammation, which could be targeted to treat different inflammatory diseases and conditions, according to a recent study published in the Journal of Clinical Investigation.
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Checkpoint Inhibitor Plus Chemotherapy Improves Outcomes for Hodgkin Lymphoma
Adding a checkpoint inhibitor to conventional chemotherapy improved outcomes for patients with relapsed or refractory classic Hodgkin lymphoma, according to a Northwestern Medicine phase II clinical trial published in JAMA Oncology.
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Combining Epigenetic and Metabolic Approaches for Targeted Cancer Treatment
Northwestern Medicine scientists have identified a novel vulnerability in a subset of genes commonly mutated in cancer, according to a study recently published in The Journal of Clinical Investigation.
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Developing New Nanoparticle Treatments for Brain Tumors
Northwestern Medicine investigators have developed a novel nanoparticle treatment for glioblastoma, according to a study published in Nature Communications.
