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Using Cancer’s Strength to Fight Against It
In findings published in Nature, scientists may have found a way around the limitations of engineered T-cells by borrowing a few tricks from cancer itself.
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Study Identifies Molecular Mechanisms of Rare Neurodevelopmental Disorder
Investigators from the laboratory of Alicia Guemez-Gamboa, PhD, assistant professor of Neuroscience, have discovered new molecular mechanisms of PACS1 syndrome, a rare neurodevelopmental disorder, according to findings published in Nature Communications.
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Survey Shows Leadership and Peer Support Essential for Resident Success
Residents are more likely to flourish in their training programs and daily lives when peer-support is strong and leadership prioritizes residents’ wellbeing, according to results from a multi-institutional survey published in Annals of Internal Medicine.
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Nobel Laureate and World-Renowned Geneticist to Speak at 2024 Commencement
Michael S. Brown, MD, director of the Jonsson Center for Molecular Genetics and Regental Professor at the University of Texas, Southwestern Medical School, will address graduates and their guests at Feinberg’s 165th commencement ceremony on Monday, May 13.
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Investigating Methods for Preventing Pancreatitis after Endoscopy
Anti-inflammatory drugs alone are not sufficient to prevent pancreas inflammation following a common endoscopic procedure, according to a study recently published in The Lancet.
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Transcription Factors Influence Insulin-Producing Beta Cells
A recent study from the laboratory of Joseph Bass, MD, PhD, has revealed how transcription factors within individual cells influence the identity and function of insulin-producing beta cells in the pancreas, according to findings published in Cell Metabolism.
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COVID-19 Vaccines Highly Effective for Children During Delta and Omicron Waves, Study Finds
The Pfizer BioNTech BNT162b2 vaccine was highly effective in preventing severe COVID-19 infections in children and adolescents during the Delta and Omicron variants, according to a large, national study recently published in the Annals of Internal Medicine.
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As Patients Live Longer, New Criteria Needed for Prostate Cancer Trials
A lack of cancer progression could be used as a surrogate for overall survival in newly metastatic prostate cancer clinical trials, according to a new meta-analysis published in the Journal of Clinical Oncology.
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New Anti-Blood Clotting Drug May Lower Risk of Recurrent Strokes
An experimental drug designed to block blood-clotting proteins may slightly lower the risk of recurrent strokes, according to a dose-finding trial published in The Lancet Neurology.
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Decorated Nanoparticles Prevent Allergic Reactions
Northwestern University scientists have developed the first selective nanoparticle therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.
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Experimental Drug May Slow Childhood Brain Tumors
The drug tovorafenib may halt the growth of or shrink some childhood brain tumors, according to a clinical trial published in Nature Medicine.
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New Cause of Neuron Death in Alzheimer’s Discovered
A new Northwestern Medicine study has identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains.
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‘Father of Microbiome Research’ Awarded 2024 Nemmers Prize in Medical Science
Jeffrey Gordon, MD, a distinguished university professor at Washington University in St. Louis, who is often referred to as the “father of microbiome research,” is the recipient of the 2024 Mechthild Esser Nemmers Prize in Medical Science at Northwestern University.
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New 3D Spatial Approach Reveals Interactive View of Glioblastoma and Therapeutic Targets
A multidisciplinary team of investigators has developed a first-of-its-kind interactive 3D spatial approach that reveals new therapeutic targets and provides a comprehensive three-dimensional view of glioblastoma tumors, detailed in a recent study published in Cell.
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Northwestern Medical Orchestra Sees Strong Growth, Unites Feinberg and Bienen
The Northwestern Medical Orchestra entered its seventh year with growth in participants and audience alike, and a performance of a composition by Bienen School of Music’s new dean, Jonathan Bailey Holland.
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Nearly 40% of Type 2 Diabetes Patients Stop Taking Their Second-Line Medication
Nearly two-thirds of patients with diabetes either discontinued their second-line medication, switched to a different medication class or intensified their treatment, according to a recent study.
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Novel Protein Interactions May Serve as Biomarker for Heart Disease
Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.
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Novel Regulator of Immune Evasion in Cancer Identified
Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
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Neural Mechanisms May Serve as Therapeutic Target for Depression
A recent study published in Molecular Psychiatry has identified previously unknown alterations in neural connectivity that promote psychomotor disturbance — a slowing or reduction in movement — in individuals with major depressive disorder.
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Mustanski Appointed as Advisor to NIH Director
Brian Mustanski, PhD, director of the Institute for Sexual and Gender Minority Health and Wellbeing, has been appointed to the Advisory Committee to the Director of National Institutes of Health.
