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Pioneering Automated Proteoform Imaging
Investigators led by Neil Kelleher, PhD, have developed an automated technique for imaging proteoforms in ovarian cancer, according to results published in Nature Communications.
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Study Finds Antidiabetic Drug Effective for Weight-Loss
Tirzepatide, an antidiabetic drug, was found to be effective in helping individuals who are overweight or have obesity and without diabetes lose weight in combination with other lifestyle changes, according to a recent clinical trial published in Nature Medicine.
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New Chicago Biopharma Hub Will Accelerate Timeline from Medical Discovery to Patient Delivery
A new partnership, the Chicago Biomedical Consortium Hub for Innovative Technology and Entrepreneurship in the Sciences, will help Chicago inventors transform their research into commercial products.
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Feinberg Scientists Make New Discoveries at the Forefront of Food Allergy Research
Though treatments for allergies have historically been slow-going, recent research by Feinberg investigators has provided new hope for the future of allergy management.
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Addressing the Need to Treat Hepatitis C in Pregnancy and Infancy
An innovative treatment plan for pregnant women is now being offered by Northwestern Medicine and Lurie Children’s Hospital, treating Hepatitis C during the course of prenatal care.
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One Sleepless Night Can Rapidly Reverse Depression for Several Days
Northwestern scientists have discovered the cause of the ‘punch-drunk’ feeling associated with sleep deprivation, and have found that it also increased dopamine and synaptic plasticity in the brain.
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Developing Custom AI Language Models to Interpret Chest X-Rays
Northwestern Medicine scientists have developed an artificial intelligence (AI) tool able to interpret chest X-rays with accuracy rivalling that of a human radiologist, according to findings published in JAMA Network Open.
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‘Super Melanin’ Heals Skin Injuries From Sunburn, Chemical Burns
A newly developed synthetic melanin, mimicking the natural melanin in human skin, can be applied topically to injured skin, where it accelerates wound healing.
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Exploring Transcription Elongation Control in Development, Disease and Aging
In a recent article published in Molecular Cell, the laboratory of Ali Shilatifard, PhD, provided a comprehensive overview of the current understanding of the elongation stage of DNA transcription and how its dysregulation is associated with developmental defects, disease and aging.
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Novel Therapy Extends Survival in Metastatic Cancer
Northwestern Medicine investigators have identified a novel therapeutic agent that is effective in treating metastatic cancer and brain metastases, according to a recent study published in the Journal of Clinical Investigation.
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Clements Receives AAFP Family Medicine Award
Deborah Clements, MD, the chair and the Nancy and Warren Furey Professor of Family and Community Medicine, has been honored with the American Academy of Family Physicians’ Thomas W. Johnson Award for her significant contributions to family medicine education.
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Improving Nanotherapeutic Vaccine Delivery
Northwestern Medicine scientists have developed a more effective way of creating nanotherapeutic vaccines and medicines, according to a study published in ACS Nano.
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New $24 Million Grant to Measure Child Health Outcomes
Northwestern University has been awarded a $24 million grant to standardize measurement tools used to evaluate childhood health nationwide as part of the National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program.
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Study Identifies Genetic Cause for Some Brain Tumors
Scientists have uncovered a genetic explanation for a subset of common brain tumors, according to a study published in Nature Communications.
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Developing New Approaches for Spinal Cord Injury
Northwestern Medicine scientists have developed a molecular “scaffold” capable of enhancing electrical activity and growth in neurons, which may prove useful in treating spinal cord injuries, per results published in ACS Nano.
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Identifying Molecular Culprits Underlying Organ Rejection
Investigators have identified how bacterial infection can alter immune response to precipitate organ rejection in mice, findings which may prove useful for improving transplant tolerance in humans, according to a recent study published in the Journal of Clinical Investigation.
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Mutations in 11 Genes Linked to Deadly Prostate Cancer
Scientists have linked mutations in 11 genes with aggressive prostate cancer, according to the largest-ever study of its kind recently published in JAMA Oncology.
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Study Discovers New Subset of Retinal Neurons Impacting Vision
Investigators have discovered a new subtype of interneurons in the retina that allows the eye to see and identify objects better in both the light and in the dark, dismantling previous notions about the inner workings of the retina, according to a Northwestern Medicine study.
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Combining Immunotherapy and Radiation in Soft Tissue Sarcoma
Combining immunotherapy with radiation may be a promising treatment option for patients with advanced soft tissue sarcoma, according to the results of a Northwestern Medicine clinical trial published in JAMA Oncology.
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Protein-Like Polymers Illuminate the Path to Macular Degeneration Treatment
A new Northwestern study details the use of protein-like polymers to potentially combat neovascular age-related macular degeneration, a leading cause of blindness.