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Study Identifies Novel Regulators of Hippocampal Overactivity
Reduced expression of specific calcium channels impaired electrical signaling between neurons and contributed to the onset of behaviors associated with neurodevelopmental disorders and seizure susceptibility in mouse models, according to a Northwestern Medicine study.
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Lecture Highlights Importance of Physical Exam Skills
The Feinberg Academy of Medical Educators recently hosted Brian Garibaldi, MD, associate professor of Medicine at Johns Hopkins University, who visited Northwestern to lead a workshop and lecture on the importance of the physical exam as part of the TIME (Today’s Innovations in Medical Education) lecture series.
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Study Identifies New Mechanisms Driving Genomic Instability
A recent Northwestern Medicine study has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of biomarkers and targeted therapies for cancer.
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Coaxing Hair Growth in Aging Hair Follicle Stem Cells
Northwestern scientists discovered how to soften hair follicle stem cells to enable them to grow hair again, according to a study published in Proceedings of the National Academy of Sciences.
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New Therapeutic Target for Osteoarthritis Identified
Investigators have discovered that a subset of sensory neurons promote osteoarthritis-related joint pain and inflammation, suggesting a new therapeutic target for pain management, according to findings published in Nature Communications.
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Largest Cell Map of Human Lung Reveals Insights Into Disease
Northwestern Medicine scientists helped develop the largest and most comprehensive cell map of the human lung in a recent study published in Nature Medicine.
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McNally Honored with Walder Award
Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, has been awarded the 2023 Martin E. and Gertrude G. Walder Award for Research Excellence.
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Biological Aging Increases Risk of Depression, Anxiety in Adults
Advanced biological aging may increase the risk of depression or anxiety in midlife for older adults, according to a recent study published in Nature Communications.
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Developing New Nanoparticle Treatments for Brain Tumors
Northwestern Medicine investigators have developed a novel nanoparticle treatment for glioblastoma, according to a study published in Nature Communications.
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Newly Discovered Mechanisms Increase Chemotherapy Resistance in Breast Cancer
Northwestern Medicine investigators have discovered novel features of circulating tumor stem cells that can promote chemotherapy evasion and metastasis in triple-negative breast cancer, according to a recent study.
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Improving Cancer Detection for Women with Dense Breasts
The use of ultrasound screening and 3D mammography only slightly increases the detection rate of breast cancer in women with dense breasts, according to a prospective multicenter study published in the Journal of Clinical Oncology.
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Transcription Factor Prevents Bone Frailty in Chronic Kidney Disease
Northwestern Medicine investigators have discovered that the overexpression of a specific transcription factor prevented bone loss in mouse models with complications from chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation.
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Study Establishes Fluctuating ’Gating’ Mechanisms Supporting Flexible Behavior
A study led by Elizabeth Johnson, PhD, has established fluctuating “gating” mechanisms that support flexible behavior and working memory in humans, findings recently published in Nature Communications.
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Discussing New Frontiers in Biomedicine
An expert panel of Northwestern leaders recently explored hot topics in longevity, AI, regenerative medicine, bioelectronics and new approaches to cancer treatment.
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Reducing Seizures After Brain Tumor Treatment
Northwestern Medicine investigators have shown that inhibiting a mutated gene can reduce seizure activity in adult-type diffuse gliomas, according to a study published in the Journal of Clinical Investigation.
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Northwestern Accepting Nominations for $350,000 Nemmers Prize in Medical Science
Northwestern University is accepting nominations for its $350,000 Mechthild Esser Nemmers Prize in Medical Science.
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Genetic Mutation Responsible for Rare Neurodevelopmental Disorder Identified
Using zebrafish models, investigators have discovered that MAP4K4 genetic variants cause neurodevelopmental delays and other physical abnormalities, demonstrating a potential therapeutic target for treating the disorder in humans, according to findings published in Science Advances.
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Celebrating Advances in Alzheimer’s Research and Clinical Care
Attendees gathered on May 11 for Alzheimer Day, an annual event hosted by the Mesulam Center for Cognitive Neurology and Alzheimer’s Disease to showcase dementia and aging research conducted throughout Northwestern and bring those discoveries to the community.
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Understanding How Hormones Influence Anemia
Northwestern Medicine scientists have uncovered how peptides produced by bones during inflammation prevent anemia in mice, according to a recent study published in the journal Blood.
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Groundbreaking Geneticist Delivers Epigenetics Lecture
Huda Yahya Zoghbi, MD, the inaugural winner of the 2016 Mechthild Esser Nemmers Prize in Medical Science at Northwestern University, returned to Feinberg on Monday as part of the Simpson Querrey Institute for Epigenetics Distinguished Lecturer Series.
