Category: Scientific Advances
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Physiological Factors Reshape How Drugs and Proteins Interact
A new Northwestern Medicine study has demonstrated that proteins studied in simplified laboratory conditions don’t behave the same way in the human body, according to the study published in Nature Structural and Molecular Biology.
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Hormone Impacts Red Blood Cell Production in Anemia
Northwestern Medicine scientists have discovered that the hormone FGF23 reduces the production of red blood cells and may contribute to the development of anemia of chronic kidney disease, according to a recent study published in Blood.
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Overlooked DNA Structures Help Organize the Genome
Northwestern Medicine scientists have discovered that little-studied DNA structures play a central role in organizing the human genome and controlling gene activity, according to a new study published in the Proceedings of the National Academy of Sciences.
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‘Toxic’ Molecule Plays Vital Role in Gene Regulation and Development
A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions.
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Policing Plagiarism of Ideas in Generative AI-Assisted Research Writing
A new publication argues that AI-assisted plagiarism in manuscript writing harms the research environment by eroding trust among scientists, misrepresenting the origin and authenticity of scholarly work, and discouraging innovation and original inquiry.
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New Experimental Method Reveals Protein Energy Landscapes on Larger Scale
Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein domains on a uniquely large scale, which may improve data-driven modeling, biology and protein engineering, as detailed in a recent study published in Nature.
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Spatial Transcriptomics Guides Inflammatory Bowel Disease Research
A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the development of inflammatory bowel diseases, as detailed in a recent study published in Nature Communications.
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New Tool Collects Biology Data into Cellular Atlases
A new computational method could dramatically accelerate efforts to map the body’s cells in space, according to a study published in Nature Genetics.
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Digital Archive Reveals How Research Agencies Fund Scientific Projects
A new digital archive developed by Northwestern scientists reveals how state-supported research funding agencies cooperate with the scientific community to decide to fund scientific research projects and support scientific innovation, as detailed in a recent study.
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Printed Neurons Communicate With Living Brain Cells
Northwestern scientists have developed flexible, low-cost devices that generate electrical signals realistic enough to activate living brain cells.
