Category: Scientific Advances
-
Trashing Cancer’s ‘Undruggable’ Proteins
Northwestern scientists have developed polymers capable of grabbing proteins and directing them to the cell’s waste-disposal machinery, potentially triggering cancer cell death.
-
Targeting Cellular Mechanisms May Improve Immune Response in Chronic Infections
Northwestern Medicine scientists have identified cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve therapeutic strategies for controlling chronic infection, according to a recent study.
-
AI Model May Improve RNA Sequencing Research
Scientists in the laboratory of Rendong Yang, PhD, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more accurately than conventional approaches, as detailed in a recent study published in Nature Communications.
-
Cells’ Systems Cooperate to Form ‘Scaffolding’ During Egg Development
A Northwestern Medicine study has shed light on one of the most intricate construction projects in biology: how cells build and coordinate the internal scaffolding needed to create a healthy egg, according to a recent study published in the Journal of Cell Biology.
-
New Underlying Mechanisms May Support Proper Transcriptional Regulation and Improve Targeted Therapies
Northwestern Medicine scientists have discovered new mechanisms underlying transcriptional initiation and elongation control that support proper gene expression, which may inform targeted therapeutic approaches for many diseases, according to a recent study published in Molecular Cell.
-
Novel Mechanism Regulates Essential Enzyme Production in Kidneys
Scientists have discovered previously unknown cellular mechanisms that regulate the production of renin, an essential enzyme in the kidney, findings that could improve the understanding of how the kidney regulates its function and how chronic kidney disease develops, according to a recent study published in Cell.
-
Understanding the Link Between Nucleotide Metabolism and Chromatin Assembly
A Northwestern Medicine study has revealed a connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, according to findings published in Molecular Cell.
-
Scientists Map the Human Genome in 4D
In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome’s three‑dimensional organization across time and space, according to a new study published in Nature.
-
2025 in Scientific Imagery
From elucidating cellular mechanisms underlying tissue regeneration to developing novel biomaterials to improve organ function, Feinberg investigators have provided stunning new snapshots of biological processes invisible to the naked eye.
-
Exploring the Connection Between Gene Expression and Aging
Northwestern Medicine scientists have discovered how molecular “traffic controllers” in cells influence aging and cellular senescence — a state where cells stop dividing but remain metabolically active.
