Category: Scientific Advances
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Unlocking New Methods for Bone Regeneration
Northwestern Medicine scientists have pioneered a new method to enhance bone regeneration therapies, as detailed in a study published in Nature Communications.
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Memories Drift Across Neurons Over Time
In a new study published in Nature, Northwestern neurobiologists have found that the brain’s internal GPS changes each time we navigate a familiar, static environment.
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Mitochondria Support T-cells Proliferation and Memory Formation
Investigators led by Navdeep Chandel, PhD, have discovered how mitochondrial metabolism supports T-cell proliferation and also prevents T-cell exhaustion in cancer and chronic infection, according to a recent study published in Nature Immunology.
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Novel Molecular Mechanisms Inform Targeted Therapies for Chronic Kidney Disease
A recent Northwestern Medicine study has identified novel molecular mechanisms by which genetic mutations in the PKD2 gene cause the most common type of polycystic kidney disease, according to findings published in Proceedings of the National Academy of Sciences.
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Novel Mechanism Reduces Epithelial Cell Damage and Loss
Northwestern Medicine scientists have discovered a previously unknown process used by epithelial cells to alleviate epithelial tissue crowding and avoid cell damage and loss, according to a recent study published in Nature Communications.
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How Hair Follicles Sense Their Environment
Northwestern Medicine scientists have discovered how cells responsible for hair growth perceive physical forces in their environment and utilize this information to regulate their behavior, according to a study published in Science Advances.
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New ‘Molecular GPS’ Will Fast-Track Drug Discovery
Scientists at Northwestern University have developed the largest open-access resource of its kind to help investigators shave off months of early-stage drug development time, detailed in research published in Science Advances.
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Developing New Methods to Map Brain-Wide Synaptic Changes
Scientists have developed a new method to track changes in synaptic protein lifetimes across the entire brain, according to a study published in Nature Neuroscience.
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Taking the Science to Market: Start-ups at Feinberg
This story was originally published in the June 2025 issue of the Breakthroughs newsletter. Every year at Feinberg, a handful of start-up companies are born from discoveries in the lab. Paperwork is filed for hundreds of inventions and patents; patents are issued and the process for optioning and licensing technology through Northwestern’s Innovations and New Ventures[…]
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Uncovering How Poxvirus Hijacks Host Proteins to Spread
Northwestern Medicine scientists have uncovered new details about how poxvirus hijacks its host’s protein synthesis machinery to multiply and spread, according to a study published in Nature Microbiology.
