
Scientists have discovered previously unknown cellular mechanisms that regulate the production of renin, an essential enzyme in the kidney, findings that could improve the understanding of how the kidney regulates its function and how chronic kidney disease develops, according to a recent study published in Cell.

A Northwestern Medicine study has revealed a connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, according to findings published in Molecular Cell.

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome’s three‑dimensional organization across time and space, according to a new study published in Nature.

From elucidating cellular mechanisms underlying tissue regeneration to developing novel biomaterials to improve organ function, Feinberg investigators have provided stunning new snapshots of biological processes invisible to the naked eye.

Northwestern Medicine scientists have discovered how molecular “traffic controllers” in cells influence aging and cellular senescence — a state where cells stop dividing but remain metabolically active.

Northwestern Medicine investigators have identified issues with most genomic sequence data for the Neisseria gonorrhoeae bacterium, findings that could complicate future epidemiological and pathogenesis studies, according to a recent study published in the Journal of Infectious Diseases.

The human brain is often described as the most complex network in existence, with billions of neurons exchanging signals across intricate pathways. Recent research led by Feinberg investigators is revealing how different regions of the brain coordinate and process information, and how disruptions in these networks can impact health.

Northwestern scientists have developed a wireless device that uses light to send information directly to the brain — bypassing the body’s natural sensory pathways, as detailed in a new study published in Nature Neuroscience.

A Northwestern Medicine study published in the Journal of Clinical Investigation has uncovered a connection between a well-known cancer-related protein and a major RNA modification process, which may inform new treatment strategies against prostate cancer.

Northwestern Medicine scientists have uncovered how a specific type of cell in the inner ear plays a commanding role in shaping the cellular landscape of the organ responsible for hearing, according to a study published in Science Advances.
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