Category: Disease Discoveries
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Huntington’s Disease Linked to Dysfunction of Brain Structure
Northwestern Medicine scientists have identified a link between Huntington’s disease and dysfunction of the subthalamic nucleus, a component of the basal ganglia, a group of brain structures critical for movement and impulse control.
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‘Rewired’ Cells Show Promise For Targeted Cancer Therapy
Northwestern University synthetic biologists have developed a general method for “rewiring” immune cells to help overcome immunosuppression in cancer.
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Transcription Factor Responsible for Variability in Congenital Brain Disorder
Northwestern Medicine scientists have identified one of the molecular mechanisms behind the variability of holoprosencephaly, a congenital brain malformation.
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Astrocytes May Play a Role in Parkinson’s Disease
New Northwestern Medicine research shows how astrocytes, a type of cell in the brain, may play a role in regulating a pathway that is overactive in Parkinson’s disease.
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New Insights Into Mechanisms Behind Polycystic Kidney Disease
A new study shows potential mechanisms leading to the activation of a mutated gene in autosomal dominant polycystic kidney disease.
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Investigating the Molecular Roots of Lung Disease
Chief Scott Budinger, MD, and the other scientists in Pulmonary and Critical Care Medicine tackle some of the most common — and fatal — medical conditions in the world.
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Potential Target for Treating Severe Malaria Identified
A pair of proteins that promote blood vessel formation are associated with the development of severe malaria, and they may be a target for future therapeutics, according to recent research.
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Enzyme Identified as Target Against Triple-Negative Breast Cancer
Northwestern Medicine scientists identified an enzyme as a potential new target for triple-negative breast cancer, a form of breast cancer that is associated with early tumor recurrence and significantly increased mortality rates.
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Pinpointing the Origins of Prostate Cancer
Northwestern Medicine scientists have identified a protein that acts as a marker for a population of cells that may be an origin for prostate cancers.
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A New Method to Predict Damage in Transplanted Kidneys
A Northwestern Medicine study has identified a gene set that can predict whether a transplanted kidney is at risk of damage and subsequent loss.
